Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 (Q24290619)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0070743

Interleukin 12 receptor subunit beta 1

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Interleukin 12B

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Interleukin 23 receptor

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Interleukin 12A

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Interleukin 23 subunit alpha

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Interleukin 12 receptor subunit beta 2

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interleukin-23 receptor binding

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Interleukin 23, alpha subunit p19

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Interleukin 12b

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Interleukin 12 receptor, beta 1

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author name string

B Oppmann

1

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R Lesley

2

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B Blom

3

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J C Timans

4

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Y Xu

5

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B Hunte

6

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F Vega

7

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N Yu

8

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J Wang

9

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K Singh

10

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F Zonin

11

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E Vaisberg

12

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T Churakova

13

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M Liu

14

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D Gorman

15

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J Wagner

16

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S Zurawski

17

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Y Liu

18

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J S Abrams

19

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K W Moore

20

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D Rennick

21

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R de Waal-Malefyt

22

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C Hannum

23

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J F Bazan

24

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R A Kastelein

Construction and biological characterization of an interleukin-12 fusion protein (Flexi-12): delivery to acute myeloid leukemic blasts using adeno-associated virus

25

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language of work or name

English

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publication date

November 2000

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published in

Immunity

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volume

13

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page(s)

715-25

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issue

5

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cites work

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IL-12 is dispensable for innate and adaptive immunity against low doses of Listeria monocytogenes

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Biosynthesis and posttranslational regulation of human IL-12.

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Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with mycobacterium tuberculosis

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Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin

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A bioactive designer cytokine for human hematopoietic progenitor cell expansion

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Interleukin-12 antagonist activity of mouse interleukin-12 p40 homodimer in vitro and in vivo

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Profile analysis: detection of distantly related proteins

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Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor

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Cutting edge: ectopic expression of the IL-12 receptor-beta 2 in developing and committed Th2 cells does not affect the production of IL-4 or induce the production of IFN-gamma.

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A receptor for interleukin 10 is related to interferon receptors

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Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

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Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

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New experimental approaches in retrovirus-mediated expression screening

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Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

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Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

421907

421907

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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