Interleukin 12b (Q21984529)

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mammalian protein found in Mus musculus
  • IL-23 subunit p40
  • IL-12 p40 subunit
  • interleukin-12 p40 subunit
  • IL-12 subunit p40
  • CLMF p40
  • interleukin-12 subunit beta
  • cytotoxic lymphocyte maturation factor 40 kDa subunit
  • Il12b
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Language Label Description Also known as
English
Interleukin 12b
mammalian protein found in Mus musculus
  • IL-23 subunit p40
  • IL-12 p40 subunit
  • interleukin-12 p40 subunit
  • IL-12 subunit p40
  • CLMF p40
  • interleukin-12 subunit beta
  • cytotoxic lymphocyte maturation factor 40 kDa subunit
  • Il12b

Statements

molecular function
cell component
extracellular space
determination method
IDA
IEA
ISO
13 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P43432
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IEA
retrieved
9 May 2019
stated in
Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
Interleukin-12 enhances interleukin-3 dependent multilineage hematopoietic colony formation stimulated by interleukin-11 or steel factor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
Negative regulation of Toll-like-receptor signaling by IRF-4.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
retrieved
9 May 2019
stated in
Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA
biological process
positive regulation of interferon-gamma production
determination method
IDA
IGI
IEA
IMP
ISO
6 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
ISO
retrieved
9 May 2019
stated in
Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IMP
retrieved
9 May 2019
stated in
Accessory protein-like is essential for IL-18-mediated signaling
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IGI
retrieved
9 May 2019
stated in
Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IGI
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IEA
retrieved
9 May 2019
stated in
H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P43432
determination method
IDA

Identifiers

 
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