Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas (Q22010904)

BCAR1 scaffold protein, Cas family member

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Chondroitin sulfate proteoglycan 4

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positive regulation of peptidyl-tyrosine phosphorylation

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K M Eisenmann

1

Kathryn M.

Eisenmann

1 reference

6 February 2023

J B McCarthy

2

James B.

McCarthy

1 reference

6 February 2023

M A Simpson

3

Melanie A.

Simpson

1 reference

6 February 2023

P J Keely

4

Patricia J.

Keely

1 reference

6 February 2023

J L Guan

5

Jun-Lin

Guan

1 reference

6 February 2023

K Tachibana

6

Kouichi

Tachibana

1 reference

6 February 2023

L Lim

7

Louis

Lim

1 reference

6 February 2023

E Manser

8

Ed

Manser

1 reference

6 February 2023

L T Furcht

9

Leo T.

Furcht

1 reference

6 February 2023

J Iida

10

Joji

Iida

1 reference

Integrins: versatility, modulation, and signaling in cell adhesion

6 February 2023

language of work or name

English

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publication date

December 1999

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published in

Nature Cell Biology

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volume

1

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issue

8

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page(s)

507-13

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cites work

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Integrin expression in human melanoma cells with differing invasive and metastatic properties

21 January 2018

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Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

21 January 2018

1 reference

Integrin-mediated signalling: regulation by protein tyrosine kinases and small GTP-binding proteins

21 January 2018

1 reference

Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

21 January 2018

1 reference

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

21 January 2018

1 reference

Cell surface chondroitin sulfate proteoglycans in tumor cell adhesion, motility and invasion

21 January 2018

1 reference

A role of chondroitin sulfate glycosaminoglycan binding site in alpha4beta1 integrin-mediated melanoma cell adhesion

21 January 2018

1 reference

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers

21 January 2018

1 reference

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

21 January 2018

1 reference

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

21 January 2018

1 reference

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

21 January 2018

1 reference

Cloning and characterization of a novel Cdc42-associated tyrosine kinase, ACK-2, from bovine brain

21 January 2018

1 reference

Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1.

21 January 2018

1 reference

Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates

21 January 2018

1 reference

The melanoma proteoglycan: restricted expression on microspikes, a specific microdomain of the cell surface

21 January 2018

1 reference

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

21 January 2018

1 reference

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

21 January 2018

1 reference

Requirements for localization of p130cas to focal adhesions

21 January 2018

1 reference

Regulation and function of the Rho subfamily of small GTPases

21 January 2018

1 reference

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

1 reference

Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix

21 January 2018

1 reference

Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan

21 January 2018

1 reference

Monoclonal antibody and an antibody-toxin conjugate to a cell surface proteoglycan of melanoma cells suppress in vivo tumor growth

21 January 2018

1 reference

The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

1 reference

Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis

21 January 2018

1 reference

Cell cycle-dependent activation of Ras.

21 January 2018

1 reference

A novel regulator of p21-activated kinases

21 January 2018

1 reference

Metastasis inhibition of different tumor types by purified laminin fragments and a heparin-binding fragment of fibronectin

21 January 2018

1 reference

7 January 2021

Tumor cell surface alpha 4 beta 1 integrin mediates adhesion to vascular endothelium: demonstration of an interaction with the N-terminal domains of INCAM-110/VCAM-1

1 reference

7 January 2021

1 reference

7 January 2021

1 reference

7 January 2021

Characterization of melanoma-associated surface antigens involved in the adhesion and motility of human melanoma cells

1 reference

7 January 2021

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

1 reference

7 January 2021

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

1 reference

7 January 2021

Identification of a mouse p21Cdc42/Rac activated kinase

1 reference

7 January 2021

Identifiers

DOI

10.1038/70302

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