Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. (Q40966232)

25 September 2017

Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. (English)

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25 September 2017

1 reference

W Yang

1

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25 September 2017

Q Lin

series ordinal

2

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25 September 2017

J L Guan

series ordinal

3

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25 September 2017

R A Cerione

series ordinal

4

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25 September 2017

language of work or name

English

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publication date

1 March 1999

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Journal of Biological Chemistry

25 September 2017

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25 September 2017

274

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25 September 2017

8524-8530

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25 September 2017

13

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Rho GTPases and the actin cytoskeleton

25 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

A novel Cdc42Hs mutant induces cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Cloning and characterization of a novel Cdc42-associated tyrosine kinase, ACK-2, from bovine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Identification of IQGAP as a putative target for the small GTPases, Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Identification of a putative effector for Cdc42Hs with high sequence similarity to the RasGAP-related protein IQGAP1 and a Cdc42Hs binding partner with similarity to IQGAP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Regulation of cross-linking of actin filament by IQGAP1, a target for Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross-links microfilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Integrins: versatility, modulation, and signaling in cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Multiple Grb2-mediated integrin-stimulated signaling pathways to ERK2/mitogen-activated protein kinase: summation of both c-Src- and focal adhesion kinase-initiated tyrosine phosphorylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Activation of Rac and Cdc42 by integrins mediates cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Actin cytoskeleton polymerization in Dbl-transformed NIH3T3 fibroblasts is dependent on cell adhesion to specific extracellular matrix proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Integrins in point contacts mediate cell spreading: factors that regulate integrin accumulation in point contacts vs. focal contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Protection from natural killer cell-mediated lysis by HLA-G expression on target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.13.8524

21 January 2018

Identifiers

DOI

10.1074/JBC.274.13.8524

1 reference

25 September 2017

1 reference