Jump to content

BCAR1 scaffold protein, Cas family member (Q21115283)

From Wikidata
mammalian protein found in Homo sapiens
  • BCAR1, Cas family scaffolding protein
  • BCAR1
  • BCAR1, Cas family scaffold protein
  • Cas scaffolding protein family member 1
  • breast cancer anti-estrogen resistance protein 1
  • CRK-associated substrate
  • Crk-associated substrate p130Cas
  • p130cas
  • breast cancer anti-estrogen resistance 1
edit
Language Label Description Also known as
default for all languages
No label defined
    English
    BCAR1 scaffold protein, Cas family member
    mammalian protein found in Homo sapiens
    • BCAR1, Cas family scaffolding protein
    • BCAR1
    • BCAR1, Cas family scaffold protein
    • Cas scaffolding protein family member 1
    • breast cancer anti-estrogen resistance protein 1
    • CRK-associated substrate
    • Crk-associated substrate p130Cas
    • p130cas
    • breast cancer anti-estrogen resistance 1

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    27 references
    retrieved
    8 April 2019
    stated in
    Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    CMS: an adapter molecule involved in cytoskeletal rearrangements
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Members of the Zyxin Family of LIM Proteins Interact with Members of the p130Cas Family of Signal Transducers
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    p130Cas mediates the transforming properties of the anaplastic lymphoma kinase
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Direct Binding of p130Cas to the Guanine Nucleotide Exchange Factor C3G
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Molecular basis for regulation of Src by the docking protein p130Cas
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    TRIP6 enhances lysophosphatidic acid-induced cell migration by interacting with the lysophosphatidic acid 2 receptor
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    P130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The role of protein-tyrosine phosphatase 1B in integrin signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Tyrosine phosphorylation of the CrkII adaptor protein modulates cell migration
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Calcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    NSP-Cas protein structures reveal a promiscuous interaction module in cell signaling
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Tyrosine phosphorylation of Crk-associated substrates by focal adhesion kinase. A putative mechanism for the integrin-mediated tyrosine phosphorylation of Crk-associated substrates
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Transformation Suppression by Protein Tyrosine Phosphatase 1B Requires a Functional SH3 Ligand
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Association of PTP-PEST with the SH3 domain of p130cas; a novel mechanism of protein tyrosine phosphatase substrate recognition
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cyanidin-3-Glucoside inhibits ethanol-induced invasion of breast cancer cells overexpressing ErbB2
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Simultaneous assay of Src SH3 and SH2 domain binding using different wavelength fluorescence polarization probes
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Vascular Endothelial Growth Factor (VEGF) Promotes Assembly of the p130Cas Interactome to Drive Endothelial Chemotactic Signaling and Angiogenesis
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    protein kinase binding
    determination method or standard
    IPI
    5 references
    retrieved
    8 April 2019
    stated in
    Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    CAS/Crk Coupling Serves as a “Molecular Switch” for Induction of Cell Migration
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cell adhesion regulates the interaction between the docking protein p130(Cas) and the 14-3-3 proteins
    GOA
    curator
    UniProt
    UniProt protein ID
    P56945
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P56945
    determination method or standard
    IPI
    cell component
    biological process

    Identifiers

    Ensembl protein ID
     
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    edit
                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q21115283&oldid=2022961794"