Small nuclear ribonucleoprotein D1 polypeptide (Q21133159)

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mammalian protein found in Homo sapiens

SNRPD1
small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene
small nuclear ribonucleoprotein Sm D1
snRNP core protein D1
Sm-D autoantigen

Language	Label	Description	Also known as
English	Small nuclear ribonucleoprotein D1 polypeptide	mammalian protein found in Homo sapiens	SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa pseudogene small nuclear ribonucleoprotein Sm D1 snRNP core protein D1 Sm-D autoantigen

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

LSM domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62314

Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62314

LSM domain, eukaryotic/archaea-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

Small nuclear ribonucleoprotein D1 family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

9 references

8 April 2019

Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Dynamic protein-protein interaction wiring of the human spliceosome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Hepatitis C Virus Nonstructural Protein NS3 Binds to Sm‐D1, a Small Nuclear Ribonucleoprotein Associated with Autoimmune Disease

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Multiple protein: protein interactions between the snRNP common core proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Hepatitis C Virus Nonstructural Protein NS3 Binds to Sm‐D1, a Small Nuclear Ribonucleoprotein Associated with Autoimmune Disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

U1 snRNP binding

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

determination method

4 references

17 October 2017

Molecular cloning of a cDNA encoding the human Sm-D autoantigen

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

determination method

4 references

8 April 2019

Molecular cloning of a cDNA encoding the human Sm-D autoantigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

SMN-Sm protein complex

determination method

1 reference

17 October 2017

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

determination method

3 references

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

catalytic step 2 spliceosome

determination method

1 reference

17 October 2017

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

spliceosomal tri-snRNP complex

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

U12-type spliceosomal complex

determination method

1 reference

17 October 2017

The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

determination method

1 reference

8 April 2019

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

precatalytic spliceosome

determination method

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

small nuclear ribonucleoprotein complex

determination method

1 reference

8 April 2019

cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

pICln-Sm protein complex

determination method

1 reference

17 October 2017

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

spliceosomal complex

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

commitment complex

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

determination method

1 reference

17 October 2017

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

determination method

6 references

17 October 2017

Molecular cloning of a cDNA encoding the human Sm-D autoantigen

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

Hepatitis C Virus Nonstructural Protein NS3 Binds to Sm‐D1, a Small Nuclear Ribonucleoprotein Associated with Autoimmune Disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

Hepatitis C Virus Nonstructural Protein NS3 Binds to Sm‐D1, a Small Nuclear Ribonucleoprotein Associated with Autoimmune Disease

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

determination method

7 references

8 April 2019

Molecular cloning of a cDNA encoding the human Sm-D autoantigen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Hepatitis C Virus Nonstructural Protein NS3 Binds to Sm‐D1, a Small Nuclear Ribonucleoprotein Associated with Autoimmune Disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Hepatitis C Virus Nonstructural Protein NS3 Binds to Sm‐D1, a Small Nuclear Ribonucleoprotein Associated with Autoimmune Disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Proteomic characterization of the human sperm nucleus

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

determination method

4 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5' splice site recognition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Functional organization of the Sm core in the crystal structure of human U1 snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

U4/U6 x U5 tri-snRNP complex

determination method

1 reference

8 April 2019

Molecular architecture of the human U4/U6.U5 tri-snRNP

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

U2-type precatalytic spliceosome

determination method

1 reference

8 April 2019

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

U2-type catalytic step 2 spliceosome

determination method

1 reference

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

biological process

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

mRNA processing

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

spliceosomal complex assembly

determination method

1 reference

8 April 2019

cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

import into nucleus

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

spliceosomal snRNP assembly

determination method

3 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

17 October 2017

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P62314&geneProductId=UniProtKB:P62314

determination method

spliceosomal snRNP assembly

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

mRNA splicing, via spliceosome

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P62314

determination method

LSM domain, eukaryotic/archaea-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62314

Small nuclear ribonucleoprotein D1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P62314

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000300413

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000300413

ENSP00000463568

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463568

ENSP00000463676

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463676

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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