Diverse metastable structures formed by small oligomers of α-synuclein probed by force spectroscopy (Q21132346)

17 August 2022

Allison Solanki

2

Allison

Solanki

1 reference

17 August 2022

Iveta Sosova

3

Iveta

Sosova

1 reference

17 August 2022

Miro Belov

4

Miro

Belov

1 reference

17 August 2022

Michael T Woodside

5

Michael T

Woodside

1 reference

Creative Commons Attribution 4.0 International

17 August 2022

language of work or name

English

0 references

publication date

2014

0 references

published in

PLOS One

0 references

volume

9

0 references

issue

1

0 references

page(s)

e86495

0 references

copyright license

start time

24 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Expression in drosophila of tandem amyloid β peptides provides insights into links between aggregation and neurotoxicity

12 September 2017

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Direct observation of multiple misfolding pathways in a single prion protein molecule

12 September 2017

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Supramolecular non-amyloid intermediates in the early stages of α-synuclein aggregation

12 September 2017

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The molten globule state is unusually deformable under mechanical force.

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α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

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Aggregation of α-synuclein is kinetically controlled by intramolecular diffusion

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The complex folding network of single calmodulin molecules

12 September 2017

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A soluble α-synuclein construct forms a dynamic tetramer

12 September 2017

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A diversity of assembly mechanisms of a generic amyloid fold

12 September 2017

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Single-molecule force spectroscopy of the add adenine riboswitch relates folding to regulatory mechanism

12 September 2017

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12 September 2017

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Optical trapping with high forces reveals unexpected behaviors of prion fibrils

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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alpha-Synuclein misfolding: single molecule AFM force spectroscopy study

12 September 2017

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Alpha-synuclein misfolding and neurodegenerative diseases

12 September 2017

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Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

12 September 2017

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12 September 2017

1 reference

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Single-molecule studies of protein folding.

12 September 2017

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High-resolution, single-molecule measurements of biomolecular motion

12 September 2017

1 reference

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The aggregation and fibrillation of alpha-synuclein

12 September 2017

1 reference

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Are amyloid diseases caused by protein aggregates that mimic bacterial pore-forming toxins?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Probing the mechanism of amyloidogenesis through a tandem repeat of the PI3-SH3 domain suggests a generic model for protein aggregation and fibril formation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Direct observation of the three-state folding of a single protein molecule

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Structure and dynamics of micelle-bound human alpha-synuclein

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

The unfolding kinetics of ubiquitin captured with single-molecule force-clamp techniques

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

The protein folding 'speed limit'.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

The pleated sheet, a new layer configuration of polypeptide chains

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Dynamic strength of molecular adhesion bonds

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

A mechanically stabilized receptor-ligand flex-bond important in the vasculature.

12 September 2017

1 reference

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Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Mechanical resistance in unstructured proteins.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Single-molecule atomic force microscopy force spectroscopy study of Aβ-40 interactions

30 May 2018

1 reference

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Alteration of the alpha-synuclein folding landscape by a mutation related to Parkinson's disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Contact order revisited: influence of protein size on the folding rate

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3901707

Signal-pair correlation analysis of single-molecule trajectories.

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Single-molecule assays for investigating protein misfolding and aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Detection of polyglutamine protein oligomers in cells by fluorescence correlation spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Direct observation of chaperone-induced changes in a protein folding pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Mechanics and structure of titin oligomers explored with atomic force microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

In vitro and in vivo neurotoxicity of prion protein oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Evidence for a partially folded intermediate in alpha-synuclein fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

The mechanical stability of ubiquitin is linkage dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Detection and Analysis of Protein Aggregation with Confocal Single Molecule Fluorescence Spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0086495

Reversible unfolding of individual titin immunoglobulin domains by AFM

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24475132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0086495

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