Alteration of the alpha-synuclein folding landscape by a mutation related to Parkinson's disease (Q41905102)

13 October 2017

Alteration of the alpha-synuclein folding landscape by a mutation related to Parkinson's disease (English)

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13 October 2017

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Allan Chris M Ferreon

1

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13 October 2017

Crystal R Moran

2

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13 October 2017

Josephine C Ferreon

3

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13 October 2017

Ashok A Deniz

4

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13 October 2017

language of work or name

English

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publication date

1 May 2010

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13 October 2017

4

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Angewandte Chemie International Edition

inferred from page(s)

published in

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volume

49

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13 October 2017

3469-3472

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13 October 2017

20

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Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence.

13 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Alpha-synuclein binds large unilamellar vesicles as an extended helix

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Linking folding and binding

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

alpha-Synuclein misfolding: single molecule AFM force spectroscopy study

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Structure and dynamics of micelle-bound human alpha-synuclein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Does alpha-synuclein modulate dopaminergic synaptic content and tone at the synapse?

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

alpha-Synuclein locus triplication causes Parkinson's disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

A broken alpha -helix in folded alpha -Synuclein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Alpha-synuclein in Lewy bodies

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Single-molecule FRET reveals structural heterogeneity of SDS-bound alpha-synuclein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Membrane-bound alpha-synuclein forms an extended helix: long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Broken helix in vesicle and micelle-bound alpha-synuclein: insights from site-directed spin labeling-EPR experiments and MD simulations.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Alpha-synuclein multistate folding thermodynamics: implications for protein misfolding and aggregation

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Lipid rafts mediate the synaptic localization of alpha-synuclein.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Effects of Parkinson's disease-linked mutations on the structure of lipid-associated alpha-synuclein

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2972640

Computed circular dichroism spectra for the evaluation of protein conformation

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20544898

12 December 2020

inferred from PubMed ID database lookup

Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20544898

12 December 2020

inferred from PubMed ID database lookup

Probing Protein-Chaperone Interactions with Single-Molecule Fluorescence Spectroscopy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20544898

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1002/ANIE.201000378

1 reference

release_uospy7bimff3lj64oqz5hyazli

13 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uospy7bimff3lj64oqz5hyazli

24 November 2022

mapped directly with Wikidata item

1 reference

13 October 2017

1 reference