antibacterial peptide LL-37 (Q1798192)

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peptide in Homo sapiens

• LL37
• LL-37
• CAMP(134-170)

edit

Language	Label	Description	Also known as
English	antibacterial peptide LL-37	peptide in Homo sapiens	LL37 LL-37 CAMP(134-170)

Statements

instance of

peptide

0 references

protein fragment

of

Cathelicidin antimicrobial peptide

1 reference

stated in

UniProt

part of

Antimicrobial peptides

0 references

Cathelicidin LL-37 binds to bacterial cell wall

0 references

Neutrophil degranulation

0 references

PRTN3 cleaves CAMP(31-170) to generate CAMP(134-170)

0 references

image of molecular model or crystal lattice model

Protein CAMP PDB 2FBS.png
700 × 300; 58 KB

depicts

ribbon diagram

0 references

found in taxon

Homo sapiens

0 references

encoded by

CAMP

0 references

molecular function

protein binding

determination method

IPI

1 reference

retrieved

26 September 2017

stated in

Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IPI

cell component

intracellular anatomical structure

determination method

IDA

1 reference

retrieved

26 September 2017

stated in

The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IDA

specific granule lumen

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

TAS

tertiary granule lumen

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

TAS

biological process

defense response

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

IEA

innate immune response in mucosa

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Antimicrobial peptides in the first line defence of human colon mucosa

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

IDA

innate immune response

determination method

IDA

IMP

6 references

retrieved

26 September 2017

stated in

Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IMP

retrieved

26 September 2017

stated in

FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IDA

retrieved

26 September 2017

stated in

The expression of the gene coding for the antibacterial peptide LL-37 is induced in human keratinocytes during inflammatory disorders

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IDA

retrieved

26 September 2017

stated in

Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IDA

retrieved

26 September 2017

stated in

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IDA

retrieved

26 September 2017

stated in

Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P49913&geneProductId=UniProtKB:P49913

determination method

IDA

killing by host of symbiont cells

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

IDA

defense response to bacterium

determination method

IEA

IMP

TAS

4 references

retrieved

8 April 2019

stated in

The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

TAS

retrieved

8 April 2019

stated in

Role of defensins in corneal epithelial barrier function against Pseudomonas aeruginosa traversal

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

IMP

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P49913

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

IEA

antimicrobial humoral response

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

TAS

neutrophil degranulation

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49913

determination method

TAS

exact match

https://www.uniprot.org/uniprot/P49913#PRO_0000004724

0 references

Identifiers

ChEBI ID

81664

0 references

Guide to Pharmacology Ligand ID

5527

0 references

KEGG ID

C18313

0 references

Reactome ID

R-HSA-1222622

0 references

R-HSA-6799515

0 references

R-HSA-6801013

0 references

Google Knowledge Graph ID

/g/1232jc_c

0 references

PDB structure ID

4EYC

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2FBS

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2FBU

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2FCG

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

2K6O

1 reference

stated in

UniProt

UniProt protein ID

P49913

retrieved

9 August 2016

language of work or name

English

Semantic Scholar topic ID

2745891

0 references

 

Sitelinks

Wikipedia(2 entries)

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• dewiki LL-37
• enwiki LL37

Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q1798192&oldid=1777815120"