Synthetic Biology Advanced Natural Product Discovery (Q110391777)

https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

title

Synthetic Biology Advanced Natural Product Discovery (English)

1 reference

https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

1 reference

1 reference

Junyang Wang

1

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https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

Jens Nielsen

series ordinal

2

1 reference

https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

Zihe Liu

series ordinal

3

1 reference

https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

publication date

17 November 2021

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https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

1 reference

https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

volume

11

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https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785

2 January 2022

issue

11

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2 January 2022

page(s)

785

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Creative Commons Attribution 4.0 International

2 January 2022

copyright license

start time

17 November 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Taxonomically Informed Scoring Enhances Confidence in Natural Products Annotation

2 references

https://opencitations.net/index/coci/api/v1/citations/10.3389/FPLS.2019.01329

2 February 2022

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

MRE: a web tool to suggest foreign enzymes for the biosynthesis pathway design with competing endogenous reactions in mind.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

A classification of liquid chromatography mass spectrometry techniques for evaluation of chemical composition and quality control of traditional medicines

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

WholeCellViz: data visualization for whole-cell models

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

High-throughput screening for efficient microbial biotechnology

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

The Human Intestinal Microbiome in Health and Disease

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

A roadmap for natural product discovery based on large-scale genomics and metabolomics

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Golden gate shuffling: a one-pot DNA shuffling method based on type IIs restriction enzymes

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

KBase: The United States Department of Energy Systems Biology Knowledgebase

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Structure-antifungal activity relationships of polyene antibiotics of the amphotericin B group

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

The evolution of genome mining in microbes - a review.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Enzymatic assembly of DNA molecules up to several hundred kilobases

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Deep metabolome annotation in natural products research: towards a virtuous cycle in metabolite identification

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Programming cells by multiplex genome engineering and accelerated evolution

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Transcription activator-like effector nucleases (TALENs): a highly efficient and versatile tool for genome editing

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

DNA assembly techniques for next-generation combinatorial biosynthesis of natural products

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Plazomicin: A Next-Generation Aminoglycoside

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Enhanced Heterologous Spinosad Production from a 79-kb Synthetic Multioperon Assembly

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Natural products in drug discovery: advances and opportunities

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Intrinsic antibiotic resistance: mechanisms, origins, challenges and solutions

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Using natural products for drug discovery: the impact of the genomics era.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

The BioCyc collection of microbial genomes and metabolic pathways

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

BiGG Models 2020: multi-strain genome-scale models and expansion across the phylogenetic tree

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Omics-based natural product discovery and the lexicon of genome mining.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

CANPA: Computer-Assisted Natural Products Anticipation

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Development and applications of CRISPR-Cas9 for genome engineering

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Targeted isolation and cloning of 100-kb microbial genomic sequences by Cas9-assisted targeting of chromosome segments

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Rapid and reliable DNA assembly via ligase cycling reaction

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Current approaches and challenges for the metabolite profiling of complex natural extracts

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Discovery of a Mosaic-Like Biosynthetic Assembly Line with a Decarboxylative Off-Loading Mechanism through a Combination of Genome Mining and Imaging.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Pathway optimization and key enzyme evolution of N-acetylneuraminate biosynthesis using an in vivo aptazyme-based biosensor.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

T5 exonuclease-dependent assembly offers a low-cost method for efficient cloning and site-directed mutagenesis.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Integration of Molecular Networking and In-Silico MS/MS Fragmentation for Natural Products Dereplication.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Human commensals producing a novel antibiotic impair pathogen colonization

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

The application of microfluidic-based technologies in the cycle of metabolic engineering

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Propagating annotations of molecular networks using in silico fragmentation.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

A gRNA-tRNA array for CRISPR-Cas9 based rapid multiplexed genome editing in Saccharomyces cerevisiae

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

The Pfam protein families database: towards a more sustainable future

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Innovative omics-based approaches for prioritisation and targeted isolation of natural products - new strategies for drug discovery

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

PCR-Independent Method of Transformation-Associated Recombination Reveals the Cosmomycin Biosynthetic Gene Cluster in an Ocean Streptomycete.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Bioprospecting Through Cloning of Whole Natural Product Biosynthetic Gene Clusters

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Fungal artificial chromosomes for mining of the fungal secondary metabolome

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

A whole-cell computational model predicts phenotype from genotype

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Predicted incorporation of non-native substrates by a polyketide synthase yields bioactive natural product derivatives

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

KEGG: new perspectives on genomes, pathways, diseases and drugs

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Start-Stop Assembly: a functionally scarless DNA assembly system optimized for metabolic engineering

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Identification of small molecules using accurate mass MS/MS search

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Microbial Chassis Development for Natural Product Biosynthesis

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

CRISPR interference-guided balancing of a biosynthetic mevalonate pathway increases terpenoid production

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Omics and multi-omics approaches to study the biosynthesis of secondary metabolites in microorganisms.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Single-cell and metagenomic analyses indicate a fermentative and saccharolytic lifestyle for members of the OP9 lineage

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Leveraging knowledge engineering and machine learning for microbial bio-manufacturing

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Review on natural products databases: where to find data in 2020

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Impact of single-cell genomics and metagenomics on the emerging view of extremophile "microbial dark matter".

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Genetic platforms for heterologous expression of microbial natural products

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

A systematic computational analysis of biosynthetic gene cluster evolution: lessons for engineering biosynthesis

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Strategies for cloning and manipulating natural and synthetic chromosomes

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Characterization and repurposing of the endogenous Type I-F CRISPR-Cas system of Zymomonas mobilis for genome engineering

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Global analysis of biosynthetic gene clusters reveals vast potential of secondary metabolite production in Penicillium species

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

A Review of the Microbial Production of Bioactive Natural Products and Biologics

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Building a global alliance of biofoundries

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Antimicrobials Inspired by Nonribosomal Peptide Synthetase Gene Clusters

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

CasHRA (Cas9-facilitated Homologous Recombination Assembly) method of constructing megabase-sized DNA.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Implementation of stable and complex biological systems through recombinase-assisted genome engineering

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Biosynthetic Potential of a Novel Antarctic Actinobacterium Marisediminicola antarctica ZS314T Revealed by Genomic Data Mining and Pigment Characterization

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Defining and combating antibiotic resistance from One Health and Global Health perspectives

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Genome-scale engineering of Saccharomyces cerevisiae with single-nucleotide precision

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Endogenous Type I CRISPR-Cas: From Foreign DNA Defense to Prokaryotic Engineering

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Delta Integration CRISPR-Cas (Di-CRISPR) in Saccharomyces cerevisiae

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Natural products as sources for new pesticides

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

BRENDA in 2017: new perspectives and new tools in BRENDA.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Discovery of the Streptoketides by Direct Cloning and Rapid Heterologous Expression of a Cryptic PKS II Gene Cluster from Streptomyces sp. Tü 6314

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Genome scale engineering techniques for metabolic engineering

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Discovery of human cell selective effector molecules using single cell multiplexed activity metabolomics

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

One-step sequence- and ligation-independent cloning as a rapid and versatile cloning method for functional genomics studies

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

MiYA, an efficient machine-learning workflow in conjunction with the YeastFab assembly strategy for combinatorial optimization of heterologous metabolic pathways in Saccharomyces cerevisiae.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases.

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Improved protein structure prediction using potentials from deep learning

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

CRISPR/Cas9 nuclease cleavage combined with Gibson assembly for seamless cloning

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Natural product discovery: past, present, and future

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale

2 February 2022

1 reference

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED)

2 February 2022

1 reference

29 July 2022

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Antidiabetic constituents of Dendrobium officinale as determined by high-resolution profiling of radical scavenging and α-glucosidase and α-amylase inhibition combined with HPLC-PDA-HRMS-SPE-NMR analysis

1 reference

2 November 2022

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

1 reference

2 November 2022

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

Mining and unearthing hidden biosynthetic potential

1 reference

25 October 2023

https://opencitations.net/index/coci/api/v1/references/10.3390/METABO11110785

ExoCET: exonuclease in vitro assembly combined with RecET recombination for highly efficient direct DNA cloning from complex genomes

1 reference

https://opencitations.net/index/api/v1/references/10.3390/METABO11110785

1 December 2023

Identifiers

1 reference

https://api.crossref.org/v1/works/http://dx.doi.org/10.3390/metabo11110785