Small-molecule inhibitors of human mitochondrial DNA transcription (Q104412529)

21 December 2020

Raffaella Di Lucrezia

object named as

Raffaella Di Lucrezia

series ordinal

9

1 reference

21 December 2020

Ilian Atanassov

10

1 reference

21 December 2020

Xinping Li

11

1 reference

21 December 2020

Peter Habenberger

15

1 reference

21 December 2020

Patrick Cramer

17

1 reference

21 December 2020

Peter Nussbaumer

19

1 reference

21 December 2020

Maria Falkenberg

21

1 reference

21 December 2020

Claes M. Gustafsson

22

1 reference

21 December 2020

Nils-Göran Larsson

23

1 reference

21 December 2020

1

Sarah Crunkhorn

1 reference

Europe PubMed Central

PubMed publication ID

33398166

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33398166%20AND%20SRC:MED&resulttype=core&format=json

https://mbexc.uni-goettingen.de/literature/publications/105

9 January 2021

language of work or name

1 reference

21 December 2020

16 December 2020

1 reference

21 December 2020

0 references

https://for2848.gwdguser.de/literature/publications/19

0 references

published in

Nature Reviews Drug Discovery

1 reference

Europe PubMed Central

PubMed publication ID

33398166

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33398166%20AND%20SRC:MED&resulttype=core&format=json

POLRMT does not transcribe nuclear genes.

9 January 2021

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

The amino terminal extension of mammalian mitochondrial RNA polymerase ensures promoter specific transcription initiation

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Structure of human mitochondrial RNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Structure of human mitochondrial RNA polymerase elongation complex

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Resistance Is Futile: Targeting Mitochondrial Energetics and Metabolism to Overcome Drug Resistance in Cancer Treatment

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Understanding the Intersections between Metabolism and Cancer Biology

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Mitochondrial ubiquinol oxidation is necessary for tumour growth

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Mitochondrial Metabolism as a Target for Cancer Therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Mechanism of Transcription Anti-termination in Human Mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Structural Basis of Mitochondrial Transcription Initiation

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Targeting mitochondrial RNA polymerase in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Late-onset corticohippocampal neurodepletion attributable to catastrophic failure of oxidative phosphorylation in MILON mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Schwann cell mitochondrial metabolism supports long-term axonal survival and peripheral nerve function

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Increased mitochondrial mass in mitochondrial myopathy mice

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Structural basis of mitochondrial transcription

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Defective mitochondrial protease LonP1 can cause classical mitochondrial disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

A novel intermediate in transcription initiation by human mitochondrial RNA polymerase.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Structure of paused transcription complex Pol II-DSIF-NELF

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

The exonuclease activity of DNA polymerase γ is required for ligation during mitochondrial DNA replication.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Real-time cryo-electron microscopy data preprocessing with Warp

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

RELION: implementation of a Bayesian approach to cryo-EM structure determination

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Addressing preferred specimen orientation in single-particle cryo-EM through tilting.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Features and development of Coot

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

limma powers differential expression analyses for RNA-sequencing and microarray studies

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

The PRIDE database and related tools and resources in 2019: improving support for quantification data

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Benzoyl chloride derivatization with liquid chromatography-mass spectrometry for targeted metabolomics of neurochemicals in biological samples

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021

Anion-Exchange Chromatography Coupled to High-Resolution Mass Spectrometry: A Powerful Tool for Merging Targeted and Non-targeted Metabolomics

1 reference

https://api.crossref.org/works/10.1038%2FS41586-020-03048-Z

7 January 2021