Wikidata:WikiProject COVID-19/Items/Biology
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Items related to the biology of the SARS-CoV-2 (Q82069695)
Related taxons
[edit]LinkeD by parent taxon (P171)
[edit]Some linking issues to be solved (see [1]).
Other Betacoronavirus (Q16532287)
[edit]See Wikidata:WikiProject_COVID-19/Queries#Other_Betacoronavirus_(Q16532287)
Genes, genomes, proteins and pathways
[edit]Query for SARS-CoV-2 protein complexes: https://w.wiki/MZo
Query for SARS-CoV-2 proteins fragments (that make up complexes) : https://w.wiki/MZp
Genome
[edit]- Genes:
- ORF1a polyprotein;ORF1ab polyprotein (Q88088053)
- surface glycoprotein (Q88000922)
- ORF3a protein-encoding gene (Q88088595)
- envelope protein (Q88088888)
- membrane glycoprotein (Q88089048)
- ORF6 protein (Q88089203)
- ORF7a protein (Q88089283)
- ORF7b (Q88089438)
- ORF8 protein (Q88089552)
- nucleocapsid phosphoprotein (Q88089689)
- ORF10 protein (Q88089847)
Proteins
[edit]Related resources
[edit]Query for proteins of SARS-CoV-2
[edit]Items
[edit]The following shows the maturation hierarchy, i.e., which fragments are cleaved from which precursors (Source: UniProt):
Based on https://covid-19.uniprot.org/uniprotkb/P0DTC1 and https://swissmodel.expasy.org/repository/species/2697049 (Retrieved in April 18th)
OBS: Some proteins have different aliases for different databases.
orf1ab polyprotein [SARS-Cov 2] (Q88174316) --- translated at low frequency by -1 ribosomal frameshift (Ref.: UniProt) ├── Host translation inhibitor nsp1 [SARS-CoV-2] (Q90038952) ├── Non-structural protein 2 [SARS CoV-2] (Q89006922) ├── Papain-like proteinase [SARS-CoV-2] (Q87917581) ├── Non-structural protein 4 [SARS-CoV-2] (Q90038956) ├── non-structural protein 5 [SARS-CoV-2] (Q87917582) ├── non-structural protein 6 [SARS-CoV-2] (Q88656943) ├── Non-structural protein 7 [SARS-CoV-2] (Q90038963) ├── Non-structural protein nsp8 [SARS-CoV-2] (Q97926844) ├── Non-structural protein 9 [SARS-CoV-2] (Q89686805) ├── Non-structural protein 10 [SARS CoV-2] (Q87917572) ├── RNA-directed RNA polymerase [SARS-CoV-2] (Q90042395) ├── Helicase [SARS-CoV-2] (Q90042799) ├── Non-structural protein 14 [SARS-CoV-2] (Q90042407) ├── non-structural protein 15 [SARS-CoV-2] (Q87917579) ├── non-structural protein 16 [SARS-CoV-2] (Q87917580) ORF1a polyprotein (Q88657499) --- no frameshift, high frequency (Ref.: UniProt) ├── Host translation inhibitor nsp1 [SARS-CoV-2] (Q90038952) ├── Non-structural protein 2 [SARS CoV-2] (Q89006922) ├── Papain-like proteinase [SARS-CoV-2] (Q87917581) ├── Non-structural protein 4 [SARS-CoV-2] (Q90038956) ├── non-structural protein 5 [SARS-CoV-2] (Q87917582) ├── non-structural protein 6 [SARS-CoV-2] (Q88656943) ├── Non-structural protein 7 [SARS-CoV-2] (Q90038963) ├── Non-structural protein nsp8 [SARS-CoV-2] (Q97926844) ├── Non-structural protein 9 [SARS-CoV-2] (Q89686805) ├── Non-structural protein 10 [SARS CoV-2] (Q87917572) ├── Non-structural protein 11 [SARS CoV-2] (Q104500452) spike glycoprotein [SARS-CoV-2] (Q87917585) ├── Spike protein S1 [SARS-CoV-2] (Q90081967) ├── Spike protein S2 [SARS-CoV-2] (Q90082228) ├── Spike protein S2' [SARS-CoV-2] (Q90082500) Viroporin 3a (Q88200603) envelope protein [SARS-CoV-2] (Q88655710) membrane protein [SARS-CoV-2] (Q88656821) ORF6 protein [SARS-CoV-2] (Q89226299) Protein 7a [SARS-CoV-2] (Q88658500) Protein non-structural 7b [SARS-CoV-2] (Q88658861) ORF8 protein [SARS-CoV-2] (Q88659350) nucleocapsid protein [SARS-CoV-2] (Q87917584) Protein ORF9b [SARS-CoV-2] (Q89597571) ORF9c protein [SARS CoV-2] (Q104520877) ORF10 protein [SARS-CoV-2] (Q89227548)
Protein families
[edit]- Replicase polyprotein 1a/1ab (Q54460717)
- Non structural protein NSP1 (Q24723394)
- Non-structural protein 3, coronavirus single-stranded poly(A) binding domain, protein family (Q83134563)
- SARS coronavirus, non-structural protein 3, N-terminal domain, protein family (Q83141119)
- Coronavirus NSP4, C-terminal domain superfamily (Q54460775)
- SARS coronavirus, non-structural protein NS6 (Q24721598)
- Non structural protein 7 family (Q83141969)
- NSP8 replicase domain, protein family (Q83135691)
- NSP9 replicase family (Q83138813)
- RNA synthesis protein NSP10, coronavirus, protein family (Q83140204)
- NSP11, protein family (Q83140150)
- Nsp15, N-terminal domain, protein family (Q88084055)
- Coronavirus non-structural protein NSP16 family (Q83141753)
- RNA polymerase, N-terminal domain, coronaviral, protein family (Q83145581)
- Coronaviridae zinc-binding domain, protein family (Q83132634)
- Coronavirus S2 glycoprotein family (Q83135478)
- Coronovirus spike glycoprotein, heptad repeat 2 domain superfamily (Q24773539)
- betacoronaviruses spike protein (Q81490886)
- Coronavirus S1 glycoprotein family (Q83145544)
- Coronavirus S2 glycoprotein family (Q83135478)
- Human SARS Coronavirus Viroporin (Q67598143)
- Severe acute respiratory syndrome coronavirus 3b protein (Q24772345) (in SARS but not in SARS-Cov-2)
- betacoronaviruses E protein (Q89037117)
- betacoronaviruses M protein family (Q89190192)
- SARS coronavirus X4-like domain, protein family (Q83136559)
- Coronavirus nonstructrual NS8 (Q24774132)
- betacoronaviruses nucleocapsid protein family (Q89257221)