Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation (Q94948758)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32415279%20AND%20SRC:MED&resulttype=core&format=json

20 May 2020

title

Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation (English)

1 reference

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20 May 2020

author name string

Valentina C Sladky

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32415279%20AND%20SRC:MED&resulttype=core&format=json

20 May 2020

Andreas Villunger

series ordinal

2

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20 May 2020

publication date

15 May 2020

1 reference

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Cell Death & Differentiation

20 May 2020

published in

1 reference

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Caspases in Cell Death, Inflammation, and Disease

20 May 2020

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Metabolic control of oocyte apoptosis mediated by 14-3-3zeta-regulated dephosphorylation of caspase-2

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7 January 2021

14-3-3 protein binding blocks the dimerization interface of caspase-2

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7 January 2021

14-3-3 protein masks the nuclear localization sequence of caspase-2

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7 January 2021

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ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P

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7 January 2021

SREBPs: metabolic integrators in physiology and metabolism

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7 January 2021

Caspase-2 and p75 neurotrophin receptor (p75NTR) are involved in the regulation of SREBP and lipid genes in hepatocyte cells

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7 January 2021

IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2.

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7 January 2021

ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis.

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7 January 2021

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7 January 2021

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7 January 2021

Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Tumors Following Chronic Liver Injury

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7 January 2021

E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

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7 January 2021

Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis

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7 January 2021

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

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7 January 2021

Osteoimmunology: interplay between the immune system and bone metabolism

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7 January 2021

A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation

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7 January 2021

DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells

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7 January 2021

Involvement of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts

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7 January 2021

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7 January 2021

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7 January 2021

Caspase-2 modulates osteoclastogenesis through down-regulating oxidative stress

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7 January 2021

Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts

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7 January 2021

Caspase-2 is required for skeletal muscle differentiation and myogenesis.

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7 January 2021

Myoblast fusion: lessons from flies and mice

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7 January 2021

Caspase 3 activity is required for skeletal muscle differentiation

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7 January 2021

Temporal activation of XRCC1-mediated DNA repair is essential for muscle differentiation.

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7 January 2021

P21 deficiency delays regeneration of skeletal muscular tissue

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7 January 2021

Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks

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7 January 2021

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7 January 2021

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7 January 2021

Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop

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7 January 2021

Caspase-2: the orphan caspase.

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7 January 2021

Caspase 2 in apoptosis, the DNA damage response and tumour suppression: enigma no more?

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7 January 2021

Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation

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7 January 2021

Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling

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7 January 2021

A non-apoptotic role for caspase-9 in muscle differentiation

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7 January 2021

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD

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7 January 2021

The PIDDosome mediates delayed death of hippocampal CA1 neurons after transient global cerebral ischemia in rats

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7 January 2021

RAIDD aggregation facilitates apoptotic death of PC12 cells and sympathetic neurons

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7 January 2021

Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice.

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7 January 2021

Caspase-2 cleavage of tau reversibly impairs memory

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7 January 2021

Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease.

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7 January 2021

A soluble truncated tau species related to cognitive dysfunction and caspase-2 is elevated in the brain of Huntington's disease patients

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7 January 2021

A soluble tau fragment generated by caspase-2 is associated with dementia in Lewy body disease

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7 January 2021

A soluble truncated tau species related to cognitive dysfunction is elevated in the brain of cognitively impaired human individuals

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7 January 2021

Rescuing neuronal cell death by RAIDD- and PIDD- derived peptides and its implications for therapeutic intervention in neurodegenerative diseases

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7 January 2021

Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant

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7 January 2021

Homozygous null variant in CRADD, encoding an adaptor protein that mediates apoptosis, is associated with lissencephaly.

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7 January 2021

RAIDD mutations underlie the pathogenesis of thin lissencephaly (TLIS)

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7 January 2021

Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.

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7 January 2021

Genetic mapping and exome sequencing identify variants associated with five novel diseases

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7 January 2021

The genetics of lissencephaly

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7 January 2021

Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population

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7 January 2021

Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland

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7 January 2021

No Evidence for Cardiomyocyte Number Expansion in Preadolescent Mice.

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7 January 2021

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32415279%20AND%20SRC:MED&resulttype=core&format=json

20 May 2020

1 reference