Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening (Q91776789)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31292530%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

review article

2 references

22 August 2022

Strategies in anti-Mycobacterium tuberculosis drug discovery based on phenotypic screening (English)

1 reference

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Mycobacterium tuberculosis

24 April 2020

main subject

1 reference

1 reference

2

1 reference

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24 April 2020

Guido F Pauli

12

1 reference

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24 April 2020

Scott G. Franzblau

13

1 reference

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24 April 2020

7

James B McAlpine

1 reference

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24 April 2020

author name string

Edyta M Grzelak

1

1 reference

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24 April 2020

Wei Gao

3

1 reference

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24 April 2020

Geping Cai

4

1 reference

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24 April 2020

Baojie Wan

5

1 reference

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24 April 2020

Yuehong Wang

6

1 reference

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24 April 2020

Jinhua Cheng

8

1 reference

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24 April 2020

Yingyu Jin

9

1 reference

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24 April 2020

Hanki Lee

10

1 reference

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24 April 2020

Joo-Won Suh

11

1 reference

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24 April 2020

Birgit U Jaki

14

1 reference

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24 April 2020

Sanghyun Cho

15

1 reference

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24 April 2020

publication date

11 July 2019

1 reference

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The Journal of Antibiotics

24 April 2020

1 October 2019

1 reference

22 August 2022

2 references

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24 April 2020

22 August 2022

72

1 reference

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24 April 2020

issue

10

1 reference

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24 April 2020

page(s)

719-728

1 reference

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Creative Commons Attribution

24 April 2020

copyright license

1 reference

22 August 2022

Outcomes of Bedaquiline Treatment in Patients with Multidrug-Resistant Tuberculosis

1 reference

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High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads

23 February 2021

1 reference

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Efficacy and safety of delamanid in combination with an optimised background regimen for treatment of multidrug-resistant tuberculosis: a multicentre, randomised, double-blind, placebo-controlled, parallel group phase 3 trial

23 February 2021

1 reference

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Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus

23 February 2021

1 reference

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Total Synthesis of Ecumicin.

23 February 2021

1 reference

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Structural Sequencing of Oligopeptides Aided by 1H Iterative Full-Spin Analysis.

23 February 2021

1 reference

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Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents.

23 February 2021

1 reference

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Sweet spot matching: A thin-layer chromatography-based countercurrent solvent system selection strategy

23 February 2021

1 reference

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World TB Day 2017: Advances, Challenges and Opportunities in the "End-TB" Era.

23 February 2021

1 reference

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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

23 February 2021

1 reference

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Bioautography with TLC-MS/NMR for Rapid Discovery of Anti-tuberculosis Lead Compounds from Natural Sources.

23 February 2021

1 reference

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Physiology, Biochemistry, and Applications of F420- and Fo-Dependent Redox Reactions.

23 February 2021

1 reference

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Computer-assisted 1 H NMR analysis of the anti-tuberculosis drug lead ecumicin.

23 February 2021

1 reference

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Anti-tuberculosis lead molecules from natural products targeting Mycobacterium tuberculosis ClpC1.

23 February 2021

1 reference

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The multidrug-resistant tuberculosis threat: old problems and new solutions

23 February 2021

1 reference

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Microplate Alamar Blue Assay (MABA) and Low Oxygen Recovery Assay (LORA) for Mycobacterium tuberculosis.

23 February 2021

1 reference

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Bactericidal mode of action of bedaquiline.

23 February 2021

1 reference

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The future for early-stage tuberculosis drug discovery

23 February 2021

1 reference

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Perspective: Challenges and opportunities in TB drug discovery from phenotypic screening

23 February 2021

1 reference

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The cyclic peptide ecumicin targeting ClpC1 is active against Mycobacterium tuberculosis in vivo

23 February 2021

1 reference

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Discovery and characterization of the tuberculosis drug lead ecumicin

23 February 2021

1 reference

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Essential parameters for structural analysis and dereplication by (1)H NMR spectroscopy.

23 February 2021

1 reference

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Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent

23 February 2021

1 reference

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Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

23 February 2021

1 reference

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New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects

23 February 2021

1 reference

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Structural Basis of Mycobacterial Inhibition by Cyclomarin A

23 February 2021

1 reference

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Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis.

23 February 2021

1 reference

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Platforms for antibiotic discovery

23 February 2021

1 reference

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Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action

23 February 2021

1 reference

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Efflux pumps of Mycobacterium tuberculosis play a significant role in antituberculosis activity of potential drug candidates

23 February 2021

1 reference

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SQ109 targets MmpL3, a membrane transporter of trehalose monomycolate involved in mycolic acid donation to the cell wall core of Mycobacterium tuberculosis

23 February 2021

1 reference

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Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles

23 February 2021

1 reference

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The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease

23 February 2021

1 reference

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The challenge of new drug discovery for tuberculosis

23 February 2021

1 reference

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Bioautography detection in thin-layer chromatography

23 February 2021

1 reference

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Evaluation of the Mycobacterium smegmatis and BCG models for the discovery of Mycobacterium tuberculosis inhibitors

23 February 2021

1 reference

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Optimisation of bioluminescent reporters for use with mycobacteria

23 February 2021

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Synergistic pandemics: confronting the global HIV and tuberculosis epidemics

23 February 2021

1 reference

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The mechanism of action of PA-824: Novel insights from transcriptional profiling

23 February 2021

1 reference

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PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release

23 February 2021

1 reference

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The Presumptive Identification of Antibiotics

23 February 2021

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Origin and evolution of high throughput screening

23 February 2021

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OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice

23 February 2021

1 reference

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Empirical antibacterial drug discovery--foundation in natural products

23 February 2021

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Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines

23 February 2021

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Streptomycin, a substance exhibiting antibiotic activity against gram-positive and gram-negative bacteria. 1944.

23 February 2021

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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

23 February 2021

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The structure of a mycobacterial outer-membrane channel

23 February 2021

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New antibiotics, ilamycins

23 February 2021

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A new antibiotic, azomycin

23 February 2021

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A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis.

23 February 2021

1 reference

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A study of the secondary structure of ilamycin B(1) by 300 MHz proton magnetic resonance

23 February 2021

1 reference

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A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

23 February 2021

1 reference

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

23 February 2021

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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

23 February 2021

1 reference

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Streptomycin, a Substance Exhibiting Antibiotic Activity Against Gram-Positive and Gram-Negative Bacteria.

23 February 2021

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41429-019-0205-9

inferred from DOI database lookup

7 January 2021

based on heuristic

Erratum for: Different Ways to On-Line Hyphenate Centrifugal Partition Chromatography and Mass Spectrometry: Application to Prenylated Xanthones from Garcinia mangostana

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inferred from DOI database lookup

7 January 2021

based on heuristic

In situ click chemistry generation of cyclooxygenase-2 inhibitors

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41429-019-0205-9

1 reference

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24 April 2020

1 reference

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24 April 2020

1 reference