protein kinase C zeta (Q906403)

Protein kinase-like domain superfamily

1 reference

Protein kinase C, PB1 domain, protein family

1 reference

Protein kinase C-like, phorbol ester/diacylglycerol-binding domain, protein family

1 reference

Protein kinase, C-terminal domain, protein family

1 reference

PB1 domain, protein family

1 reference

Diacylglycerol/phorbol-ester binding domain, protein family

1 reference

AGC-kinase, C-terminal domain, protein family

1 reference

Atypical Protein Kinase C zeta, catalytic domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

1 reference

13 November 2019

1 reference

13 November 2019

phospholipase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

protein domain specific binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

2 references

protein kinase activity

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

protein serine/threonine kinase activity

5 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

26 September 2017

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

26 September 2017

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

insulin receptor substrate binding

EXP

1 reference

8 April 2019

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

14-3-3 protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

potassium channel regulator activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

24 references

8 April 2019

A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Centaurin-alpha(1) associates with and is phosphorylated by isoforms of protein kinase C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

APPL proteins promote TGFβ-induced nuclear transport of the TGFβ type I receptor intracellular domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

PKCtheta cooperates with atypical PKCzeta and PKCiota in NF-kappaB transactivation of T lymphocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Protein kinase C [micro] is regulated by the multifunctional chaperon protein p32

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein-protein interactions in relation to subcellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Par-4 inhibits Akt and suppresses Ras-induced lung tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

PKCzetaII is a target for degradation through the tumour suppressor protein pVHL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Novel PKC-ζ to p47 phox interaction is necessary for transformation from blebbishields

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

mTORC2 phosphorylates protein kinase Cζ to regulate its stability and activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Pooled-matrix protein interaction screens using Barcode Fusion Genetics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

protein kinase C activity

protein serine/threonine kinase activity

TAS

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

3 references

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

26 September 2017

Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zeta

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

CCM1 regulates vascular-lumen organization by inducing endothelial polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

bicellular tight junction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

microtubule organizing center

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

apical plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

intracellular membrane-bounded organelle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

myelin sheath abaxonal region

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

protein-containing complex

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

Schaffer collateral - CA1 synapse

HDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

glutamatergic synapse

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

positive regulation of glucose import

biological process

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

insulin receptor signaling pathway

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

protein heterooligomerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

negative regulation of hydrolase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

protein kinase C signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

protein phosphorylation

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase Cdelta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

WD-repeat-propeller-FYVE protein, ProF, binds VAMP2 and protein kinase Czeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

negative regulation of insulin receptor signaling pathway

1 reference

8 April 2019

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

cell surface receptor signaling pathway

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

activation of phospholipase D activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

positive regulation of synaptic transmission

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

negative regulation of protein-containing complex assembly

TAS

1 reference

8 April 2019

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

negative regulation of peptidyl-tyrosine phosphorylation

IMP

1 reference

8 April 2019

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

cellular response to insulin stimulus

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

protein localization to plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

inflammatory response

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

positive regulation of cell-matrix adhesion

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

membrane depolarization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

positive regulation of protein transport

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

microtubule cytoskeleton organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

actin cytoskeleton reorganization

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

activation of protein kinase B activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

membrane hyperpolarization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

vesicle transport along microtubule

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

neuron projection extension

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

peptidyl-serine phosphorylation

2 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

26 September 2017

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05513&geneProductId=UniProtKB:Q05513

positive regulation of cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

peptidyl-serine phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Protein kinase C-zeta-induced phosphorylation of Ser318 in insulin receptor substrate-1 (IRS-1) attenuates the interaction with the insulin receptor and the tyrosine phosphorylation of IRS-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

intracellular signal transduction

IBA

IBA

regulation of neurotransmitter receptor localization to postsynaptic specialization membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05513

physically interacts with

arachidonic acid

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2391

language of work or name

17 August 2016

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

8142

language of work or name

English

retrieved

17 August 2016

Gene Atlas image

PBB GE PRKCZ 202178 at fs.png
732 × 530; 12 KB

0 references

has part(s)

AGC-kinase, C-terminal

1 reference

protein kinase domain

1 reference

protein kinase, ATP binding site

1 reference

protein kinase, C-terminal

1 reference

protein kinase C-like, phorbol ester/diacylglycerol-binding domain

1 reference

PB1 domain

1 reference

serine/threonine-protein kinase, active site

1 reference

diacylglycerol/phorbol-ester binding

1 reference

Atypical Protein Kinase C zeta, catalytic domain

1 reference

Protein kinase C, PB1 domain

1 reference