Mitochondrial peptides modulate mitochondrial function during cellular senescence (Q89052653)

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30 March 2020

title

Mitochondrial peptides modulate mitochondrial function during cellular senescence (English)

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30 March 2020

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Su-Jeong Kim

1

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30 March 2020

Hemal H Mehta

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30 March 2020

Junxiang Wan

3

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30 March 2020

Chisaka Kuehnemann

4

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30 March 2020

Jingcheng Chen

5

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30 March 2020

Ji-Fan Hu

6

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30 March 2020

Andrew R Hoffman

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30 March 2020

Pinchas Cohen

8

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publication date

1 June 2018

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30 March 2020

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30 March 2020

volume

10

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30 March 2020

page(s)

1239-1256

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30 March 2020

issue

6

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Increased glycolysis in ageing cultured human diploid fibroblasts

30 March 2020

cites work

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12 December 2020

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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12 December 2020

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

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12 December 2020

Humanin peptide suppresses apoptosis by interfering with Bax activation

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12 December 2020

Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis

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12 December 2020

Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays

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12 December 2020

Involvement of tyrosine kinases and STAT3 in Humanin-mediated neuroprotection

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12 December 2020

Glucose-Induced Replicative Senescence in Mesenchymal Stem Cells

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12 December 2020

Persistent alterations to the gene expression profile of the heart subsequent to chronic Doxorubicin treatment

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12 December 2020

Senescence-messaging secretome: SMS-ing cellular stress

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12 December 2020

Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130

1 reference

12 December 2020

Understanding the Warburg effect: the metabolic requirements of cell proliferation

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12 December 2020

Humanin: a novel central regulator of peripheral insulin action

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12 December 2020

Early effects of doxorubicin in perfused heart: transcriptional profiling reveals inhibition of cellular stress response genes.

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12 December 2020

Inflammatory networks during cellular senescence: causes and consequences

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12 December 2020

Humanin is expressed in human vascular walls and has a cytoprotective effect against oxidized LDL-induced oxidative stress

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12 December 2020

Humanins, the neuroprotective and cytoprotective peptides with antiapoptotic and anti-inflammatory properties.

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12 December 2020

A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice

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12 December 2020

DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria

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12 December 2020

Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice

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12 December 2020

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

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12 December 2020

Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis.

1 reference

12 December 2020

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

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12 December 2020

Oncogene-induced senescence results in marked metabolic and bioenergetic alterations

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12 December 2020

Neuroprotective Peptide humanin inhibits inflammatory response in astrocytes induced by lipopolysaccharide

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12 December 2020

Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model

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12 December 2020

Simplified evaluation of apoptosis using the Muse cell analyzer

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12 December 2020

Pharmacokinetics and tissue distribution of humanin and its analogues in male rodents

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12 December 2020

Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool

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12 December 2020

Methods of cellular senescence induction using oxidative stress

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12 December 2020

A humanin analog decreases oxidative stress and preserves mitochondrial integrity in cardiac myoblasts

1 reference

12 December 2020

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA

1 reference

12 December 2020

Humanin and age-related diseases: a new link?

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12 December 2020

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

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12 December 2020

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

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12 December 2020

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

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12 December 2020

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.

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12 December 2020

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

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12 December 2020

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

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12 December 2020

Targeting senescent cells enhances adipogenesis and metabolic function in old age

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12 December 2020

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

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12 December 2020

Mitochondria are required for pro-ageing features of the senescent phenotype.

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12 December 2020

Quantification of global mitochondrial DNA methylation levels and inverse correlation with age at two CpG sites.

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12 December 2020

The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction

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12 December 2020

CpG methylation patterns of human mitochondrial DNA

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12 December 2020

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers

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12 December 2020

MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism

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12 December 2020

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12 December 2020

Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses

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12 December 2020

From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence

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12 December 2020

The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus

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12 December 2020

Disease drivers of aging

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12 December 2020

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.

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12 December 2020

Chronic Inflammation: Accelerator of Biological Aging

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12 December 2020

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging

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12 December 2020

Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

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12 December 2020

DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology

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12 December 2020

Mitochondrial DNA Hypomethylation Is a Biomarker Associated with Induced Senescence in Human Fetal Heart Mesenchymal Stem Cells.

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12 December 2020

Cellular senescence drives age-dependent hepatic steatosis.

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12 December 2020

Aging: Cancer - an unlikely couple

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12 December 2020

Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells.

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12 December 2020

Identifiers

DOI

10.18632/AGING.101463

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30 March 2020

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30 March 2020

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