Early effects of doxorubicin in perfused heart: transcriptional profiling reveals inhibition of cellular stress response genes. (Q43201120)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

Early effects of doxorubicin in perfused heart: transcriptional profiling reveals inhibition of cellular stress response genes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Michael Zaugg

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Uwe Schlattner

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Malgorzata Tokarska-Schlattner

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Laurence Kay

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Séverine Gratia

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Rita Guzun

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Valdur Saks

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

publication date

6 January 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

298

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

R1075-88

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20053966%20AND%20SRC:MED&resulttype=core&format=json

Pharmacological and clinical aspects of heme oxygenase

16 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Immunogenicity of anthracyclines: moving towards more personalized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Reactive oxygen species-independent apoptosis in doxorubicin-treated H9c2 cardiomyocytes: role for heme oxygenase-1 down-modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Persistent alterations to the gene expression profile of the heart subsequent to chronic Doxorubicin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Enhancing the antiproliferative effect of topoisomerase II inhibitors using a polypeptide inhibitor of c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Heat shock proteins in cancer: chaperones of tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Doxorubicin selectively inhibits brain versus atrial natriuretic peptide gene expression in cultured neonatal rat myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Transcriptional consequences of topoisomerase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Pharmacological induction of Hsp70 protects apoptosis-prone cells from doxorubicin: comparison with caspase-inhibitor- and cycle-arrest-mediated cytoprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Wnt/beta-catenin-pathway as a molecular target for future anti-cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Does bulk damage to DNA explain the cytostatic and cytotoxic effects of topoisomerase II inhibitors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Anthracycline cardiotoxicity: from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Summaries of Affymetrix GeneChip probe level data

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Doxorubicin selectively inhibits muscle gene expression in cardiac muscle cells in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Transforming growth factor-beta in cancer and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Molecular mechanisms of doxorubicin-induced cardiomyopathy. Selective suppression of Reiske iron-sulfur protein, ADP/ATP translocase, and phosphofructokinase genes is associated with ATP depletion in rat cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Analysis of mitochondrial function in situ in permeabilized muscle fibers, tissues and cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Tissue-specific mtDNA lesions and radical-associated mitochondrial dysfunction in human hearts exposed to doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Time-Dependent and Tissue-Specific Accumulation of mtDNA and Respiratory Chain Defects in Chronic Doxorubicin Cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Changes in host defence induced by malignancies and antineoplastic treatment: implication for immunotherapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Early changes in myocardial antioxidant enzymes in rats treated with adriamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Cytokines are not upregulated in adriamycin-induced cardiomyopathy and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Involvement of mitogen-activated protein kinases in adriamycin-induced cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Daunorubicin-induced variations in gene transcription: commitment to proliferation arrest, senescence and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Permeabilized cell and skinned fiber techniques in studies of mitochondrial function in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Mitochondrial creatine kinase in human health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Repression of mitogen-activated protein kinase (MAPK) phosphatase-1 by anthracyclines contributes to their antiapoptotic activation of p44/42-MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Role of Multidrug Resistance Protein 2 (MRP2, ABCC2) in Alkylating Agent Detoxification: MRP2 Potentiates GlutathioneS-Transferase A1-1-Mediated Resistance to Chlorambucil Cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Role of Rho GTPases in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Reduced creatine-stimulated respiration in doxorubicin challenged mitochondria: particular sensitivity of the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Alterations in myocardial energy metabolism induced by the anti-cancer drug doxorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Multiple interference of anthracyclines with mitochondrial creatine kinases: preferential damage of the cardiac isoenzyme and its implications for drug cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

New insights into doxorubicin-induced cardiotoxicity: the critical role of cellular energetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Selective inhibition of muscle gene expression by oxidative stress in cardiac cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Significance analysis of microarrays applied to the ionizing radiation response

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Heat shock protects cardiac cells from doxorubicin-induced toxicity by activating p38 MAPK and phosphorylation of small heat shock protein 27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

The hypoxic inducible stress response as a target for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

PMP24, a gene identified by MSRF, undergoes DNA hypermethylation-associated gene silencing during cancer progression in an LNCaP model

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Inducible activation of c-Myc in adult myocardium in vivo provokes cardiac myocyte hypertrophy and reactivation of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Transcriptional analysis of doxorubicin-induced cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009

Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00360.2009