IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils (Q85337479)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25236377%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils (English)

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16 February 2020

author name string

Daisuke Kurotaki

1

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16 February 2020

Michio Yamamoto

2

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16 February 2020

Akira Nishiyama

3

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16 February 2020

Kazuhiro Uno

4

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16 February 2020

Tatsuma Ban

5

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16 February 2020

Motohide Ichino

6

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16 February 2020

Haruka Sasaki

7

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16 February 2020

Satoko Matsunaga

8

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16 February 2020

Masahiro Yoshinari

9

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16 February 2020

Akihide Ryo

10

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16 February 2020

Masatoshi Nakazawa

11

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16 February 2020

Keiko Ozato

12

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16 February 2020

Tomohiko Tamura

13

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16 February 2020

publication date

19 September 2014

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16 February 2020

published in

Nature Communications

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16 February 2020

volume

5

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16 February 2020

page(s)

4978

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https://scigraph.springernature.com/pub.10.1038/ncomms5978

16 February 2020

exact match

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Cooperation between deficiencies of IRF-4 and IRF-8 promotes both myeloid and lymphoid tumorigenesis.

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IRF-8 extinguishes neutrophil production and promotes dendritic cell lineage commitment in both myeloid and lymphoid mouse progenitors

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PU.1 level-directed chromatin structure remodeling at the Irf8 gene drives dendritic cell commitment.

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IRF8 mutations and human dendritic-cell immunodeficiency

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IFN consensus sequence binding protein/IFN regulatory factor-8 guides bone marrow progenitor cells toward the macrophage lineage.

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Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks

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c-Myc is a critical target for c/EBPalpha in granulopoiesis.

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7 January 2021

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

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7 January 2021

The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite

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Identifiers

DOI

10.1038/NCOMMS5978

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25236377%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

16 February 2020

ADS bibcode

2014NatCo...5.4978K

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