Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection (Q84185759)

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2 February 2020

title

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection (English)

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2 February 2020

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3

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2 February 2020

Raymond J Steptoe

series ordinal

4

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2 February 2020

author name string

Tracy Doan

series ordinal

1

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2 February 2020

Alice McNally

series ordinal

2

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2 February 2020

publication date

7 July 2009

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Immunology & Cell Biology

2 February 2020

published in

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volume

87

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issue

8

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page(s)

615-622

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

2 February 2020

cites work

1 reference

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7 January 2021

Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.

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7 January 2021

Conditions that induce tolerance in mature CD4+ T cells

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Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivo

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.46

7 January 2021

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

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7 January 2021

T cell tolerance to a neo-self antigen expressed by thymic epithelial cells: the soluble form is more effective than the membrane-bound form.

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7 January 2021

Central tolerance to self-antigen expressed by cortical epithelial cells

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T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

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7 January 2021

Increased CD8+ cytotoxic T cell responses to myelin basic protein in multiple sclerosis

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7 January 2021

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

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7 January 2021

Self-representation in the thymus: an extended view

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Promiscuous thymic expression of an autoantigen gene does not result in negative selection of pathogenic T cells

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7 January 2021

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

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7 January 2021

Inducible transgenic mice reveal resting dendritic cells as potent inducers of CD8+ T cell tolerance.

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7 January 2021

Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells.

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7 January 2021

Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses

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7 January 2021

A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes

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7 January 2021

Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.

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7 January 2021

Central tolerance: learning self-control in the thymus

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7 January 2021

Negative selection of the T-cell repertoire: where and when does it occur?

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https://api.crossref.org/works/10.1038%2FICB.2009.46

7 January 2021

The timing of TCR alpha expression critically influences T cell development and selection

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7 January 2021

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

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7 January 2021

Differential MHC class II presentation of a pathogenic autoantigen during health and disease

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7 January 2021

Cognate T cell help is sufficient to trigger anti-nuclear autoantibodies in naive mice

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7 January 2021

Citrullination is an inflammation-dependent process

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7 January 2021

Regulation of CD8+ T cell development by thymus-specific proteasomes

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7 January 2021

Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function

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7 January 2021

CD8+ T lymphocytes in double alpha beta TCR transgenic mice. I. TCR expression and thymus selection in the absence or in the presence of self-antigen

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.46

7 January 2021

Thymic and postthymic regulation of diabetogenic CD8 T cell development in TCR transgenic nonobese diabetic (NOD) mice

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.46

7 January 2021

Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.46

7 January 2021

T cell receptor antagonist peptides induce positive selection

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.46

7 January 2021

Both intrathymic and peripheral selection modulate the differential expression of V beta 5 among CD4+ and CD8+ T cells

1 reference

https://api.crossref.org/works/10.1038%2FICB.2009.46

7 January 2021

Herpes simplex virus-specific CD8+ T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation

1 reference

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7 January 2021

Identifiers

DOI

10.1038/ICB.2009.46

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581919%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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