Analysis of the role of Rab27 effector Slp4-a/Granuphilin-a in dense-core vesicle exocytosis (Q82533435)

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16 January 2020

title

Analysis of the role of Rab27 effector Slp4-a/Granuphilin-a in dense-core vesicle exocytosis (English)

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16 January 2020

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1

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16 January 2020

author name string

Eiko Kanno

series ordinal

2

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16 January 2020

publication date

1 January 2005

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16 January 2020

published in

Methods in Enzymology

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16 January 2020

volume

403

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16 January 2020

page(s)

445-457

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Pancreatic beta-cell protein granuphilin binds Rab3 and Munc-18 and controls exocytosis

16 January 2020

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MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes

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Synaptotagmin-like protein (Slp) homology domain 1 of Slac2-a/melanophilin is a critical determinant of GTP-dependent specific binding to Rab27A.

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Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans

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Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2

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7 January 2021

Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells

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Versatile role of Rab27 in membrane trafficking: focus on the Rab27 effector families.

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Slac2-c (synaptotagmin-like protein homologue lacking C2 domains-c), a novel linker protein that interacts with Rab27, myosin Va/VIIa, and actin

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A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms

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Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins

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Functional diversity of C2 domains of synaptotagmin family. Mutational analysis of inositol high polyphosphate binding domain.

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Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X

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Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain

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Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells

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7 January 2021

The calcium-binding loops of the tandem C2 domains of synaptotagmin VII cooperatively mediate calcium-dependent oligomerization.

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Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells

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Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport

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Alternative splicing isoforms of synaptotagmin VII in the mouse, rat and human

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Rabphilin and Noc2 are recruited to dense-core vesicles through specific interaction with Rab27A in PC12 cells

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The small GTPase Rab27B regulates amylase release from rat parotid acinar cells

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The roles of Rab27 and its effectors in the regulated secretory pathways

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Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes.

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7 January 2021

The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain

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7 January 2021

Synaptotagmin-like protein 5: a novel Rab27A effector with C-terminal tandem C2 domains

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pEF-BOS, a powerful mammalian expression vector

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Synaptotagmin V is targeted to dense-core vesicles that undergo calcium-dependent exocytosis in PC12 cells

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7 January 2021

A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport

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Granuphilin modulates the exocytosis of secretory granules through interaction with syntaxin 1a

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7 January 2021

Rab27 effector granuphilin promotes the plasma membrane targeting of insulin granules via interaction with syntaxin 1a.

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Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells

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7 January 2021

The Rab27a/granuphilin complex regulates the exocytosis of insulin-containing dense-core granules

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Rab proteins as membrane organizers

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16473610%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

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