Effect of glutamine synthesis inhibition with methionine sulfoximine on the nitric oxide-cyclic GMP pathway in the rat striatum treated acutely with ammonia: a microdialysis study (Q80861407)

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scientific article published on 29 August 2007

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English	Effect of glutamine synthesis inhibition with methionine sulfoximine on the nitric oxide-cyclic GMP pathway in the rat striatum treated acutely with ammonia: a microdialysis study	scientific article published on 29 August 2007

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Europe PubMed Central

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4 January 2020

Effect of glutamine synthesis inhibition with methionine sulfoximine on the nitric oxide-cyclic GMP pathway in the rat striatum treated acutely with ammonia: a microdialysis study (English)

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Europe PubMed Central

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4 January 2020

Michał Mączewski

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4 January 2020

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4 January 2020

Andrzej Beresewicz

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Andrzej Beresewicz

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4 January 2020

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Wojciech Hilgier

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4 January 2020

Michal Wegrzynowicz

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4 January 2020

Simo S Oja

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4 January 2020

Pirjo Saransaari

6

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4 January 2020

publication date

29 August 2007

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4 January 2020

Neurochemical Research

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4 January 2020

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4 January 2020

2

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4 January 2020

267-272

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4 January 2020

https://scigraph.springernature.com/pub.10.1007/s11064-007-9455-1

0 references

Flumazenil does not affect the increase in rat hippocampal extracellular glutamate concentration produced during thioacetamide-induced hepatic encephalopathy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of glial glutamine release to the extracellular fluid studied in vivo by NMR and microdialysis in hyperammonemic rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tonic activation of NMDA receptors by ambient glutamate of non-synaptic origin in the rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of methionine sulfoximine analogs on the synthesis of glutamine and glutathione: possible chemotherapeutic implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ammonia-induced production of free radicals in primary cultures of rat astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between L-arginine and L-glutamine change endothelial NO production. An effect independent of NO synthase substrate availability.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decrease in glutathione levels of kidney and liver after injection of methionine sulfoximine into rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucosamine Inhibits Inducible Nitric Oxide Synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic GMP in blood and minimal hepatic encephalopathy: fine-tuning of the diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein tyrosine nitration in hyperammonemia and hepatic encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral blood flow and the development of ammonia-induced brain edema in rats after portacaval anastomosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular brain glutamate during acute liver failure and during acute hyperammonemia simulating acute liver failure: an experimental study based on in vivo brain dialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of brain glutamine accumulation prevents cerebral edema in hyperammonemic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taurine reduces ammonia- and N-methyl-D-aspartate-induced accumulation of cyclic GMP and hydroxyl radicals in microdialysates of the rat striatum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sources of oxygen radicals in brain in acute ammonia intoxication in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamine: a Trojan horse in ammonia neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of methionine sulfoximine on the glutamine and glutamate content and cell volume in rat cerebral cortical slices: involvement of mechanisms not related to inhibition of glutamine synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of cerebral cortical glutathione synthesis by ammonia in vivo and in cultured glial cells: the role of cystine uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of the mitochondrial permeability transition in cultured astrocytes by glutamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glutamine synthetase reduces ammonia-induced astrocyte swelling in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of transmitter amino acid levels in rat globus pallidus and neostriatum during hypoglycemia or after treatment with methionine sulfoximine or gamma-vinyl gamma-aminobutyric acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ammonium ions on synaptic transmission and on responses to quisqualate and N-methyl-D-aspartate in hippocampal CA1 pyramidal neurons in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in brain ECF amino acids in rats with experimentally induced hyperammonemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Memantine, a noncompetitive NMDA receptor antagonist improves hyperammonemia-induced encephalopathy and acute hepatic encephalopathy in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of nitric oxide and free radicals in cardioprotection by blocking Na+/H+ and Na+/Ca2+ exchange in rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of ammonia and portal-systemic shunting on brain metabolism, neurotransmission and intracranial hypertension in hyperammonaemia-induced encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoosmotic swelling increases protein tyrosine nitration in cultured rat astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persistent arterial hyperammonemia increases the concentration of glutamine and alanine in the brain and correlates with intracranial pressure in patients with fulminant hepatic failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methionine sulfoximine shows excitotoxic actions in rat cortical slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by L-glutamine of the release of endothelium-derived relaxing factor from cultured endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taurine prevents ammonia-induced accumulation of cyclic GMP in rat striatum by interaction with GABAA and glycine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial regulation of nonsynaptic extracellular glutamate in the substantia nigra.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ammonia-induced extracellular accumulation of taurine in the rat striatum in vivo: role of ionotropic glutamate receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ammonia stimulates glutamine uptake to the cerebral non-synaptic mitochondria of the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of N-methyl-D-aspartate receptors in rat brain in vivo following acute ammonia intoxication: characterization by in vivo brain microdialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Importance of glutamine for gamma-aminobutyric acid synthesis in rat neostriatum in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-enzymatic assay for determination of glutamine and glutamic acid in cerebrospinal fluid and plasma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of acute ammonia toxicity on nitric oxide (NO), citrulline-NO cycle enzymes, arginase and related metabolites in different regions of rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blocking NMDA receptors prevents the oxidative stress induced by acute ammonia intoxication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel glycine site-specific N-methyl-D-aspartate receptor antagonist prevents activation of the NMDA/NO/CGMP pathway by ammonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of permeability transition and swelling of rat brain mitochondria by glutamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Block of glutamate-glutamine cycle between astrocytes and neurons inhibits epileptiform activity in hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamine-induced free radical production in cultured astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17726645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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