Effects of IL-23 and IL-27 on osteoblasts and osteoclasts: inhibitory effects on osteoclast differentiation (Q80809164)

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3 January 2020

title

Effects of IL-23 and IL-27 on osteoblasts and osteoclasts: inhibitory effects on osteoclast differentiation (English)

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author name string

Sadahiro Kamiya

1

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3 January 2020

Chika Nakamura

2

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3 January 2020

Takeshi Fukawa

3

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3 January 2020

Katsuhiro Ono

4

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3 January 2020

Toshiyuki Ohwaki

5

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3 January 2020

Takayuki Yoshimoto

6

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Seiki Wada

7

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publication date

25 August 2007

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Journal of Bone and Mineral Metabolism

3 January 2020

published in

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volume

25

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issue

5

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page(s)

277-285

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https://scigraph.springernature.com/pub.10.1007/s00774-007-0766-8

3 January 2020

exact match

0 references

cites work

Protein expression and functional difference of membrane-bound and soluble receptor activator of NF-kappaB ligand: modulation of the expression by osteotropic factors and cytokines

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12 December 2020

The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis

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IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

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Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

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IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

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Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures

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Interleukin-3 and granulocyte-macrophage colony-stimulating factor inhibits tumor necrosis factor (TNF)-alpha-induced osteoclast differentiation by down-regulation of expression of TNF receptors 1 and 2.

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IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells

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12 December 2020

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

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12 December 2020

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

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12 December 2020

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

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12 December 2020

IL-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors: role for CD8+ T cells

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12 December 2020

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

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12 December 2020

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

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12 December 2020

Stat1-dependent synergistic activation of T-bet for IgG2a production during early stage of B cell activation

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Adjuvant activities of novel cytokines, interleukin-23 (IL-23) and IL-27, for induction of hepatitis C virus-specific cytotoxic T lymphocytes in HLA-A*0201 transgenic mice.

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IL-4 suppresses osteoclast development and mature osteoclast function by a STAT6-dependent mechanism: irreversible inhibition of the differentiation program activated by RANKL

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Induction of IgG2a class switching in B cells by IL-27.

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Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis.

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

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Interleukin-18 (interferon-gamma-inducing factor) is produced by osteoblasts and acts via granulocyte/macrophage colony-stimulating factor and not via interferon-gamma to inhibit osteoclast formation

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12 December 2020

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

1 reference

12 December 2020

Cell-to-Cell adhesion via intercellular adhesion molecule-1 and leukocyte function-associated antigen-1 pathway is involved in 1alpha,25(OH)2D3, PTH and IL-1alpha-induced osteoclast differentiation and bone resorption

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12 December 2020

Differential expression of gamma interferon mRNA induced by attenuated and virulent Mycobacterium tuberculosis in guinea pig cells after Mycobacterium bovis BCG vaccination

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12 December 2020

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

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12 December 2020

IL-27 suppresses CD28-mediated [correction of medicated] IL-2 production through suppressor of cytokine signaling 3.

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12 December 2020

Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis

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12 December 2020

IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae

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12 December 2020

STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroi

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12 December 2020

Combination of interleukin-6 and soluble interleukin-6 receptors induces differentiation and activation of JAK-STAT and MAP kinase pathways in MG-63 human osteoblastic cells

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12 December 2020

An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells

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12 December 2020

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

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12 December 2020

Potent antitumor activity of interleukin-27.

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12 December 2020

Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27.

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12 December 2020

Antiangiogenic and antitumor activities of IL-27.

1 reference

12 December 2020

10.1007/S00774-007-0766-8

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17704992%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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