Structural elements of the gamma-aminobutyric acid type A receptor conferring subtype selectivity for benzodiazepine site ligands (Q77388224)

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5 December 2019

title

Structural elements of the gamma-aminobutyric acid type A receptor conferring subtype selectivity for benzodiazepine site ligands (English)

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5 December 2019

author name string

S Renard

1

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5 December 2019

A Olivier

2

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5 December 2019

P Granger

3

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5 December 2019

P Avenet

4

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5 December 2019

D Graham

5

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5 December 2019

M Sevrin

6

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P George

7

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F Besnard

8

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5 December 2019

language of work or name

English

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publication date

1 May 1999

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Journal of Biological Chemistry

5 December 2019

published in

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5 December 2019

volume

274

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5 December 2019

issue

19

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5 December 2019

page(s)

13370-13374

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5 December 2019

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Which GABAA-receptor subtypes really occur in the brain?

21 January 2018

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Limitations of the benzodiazepine receptor nomenclature: a proposal for a pharmacological classification as omega receptor subtypes.

21 January 2018

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The benzodiazepine binding site of GABAA receptors

21 January 2018

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A review of recently-developed ligands for neuronal benzodiazepine receptors and their pharmacological activities

21 January 2018

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The major site of photoaffinity labeling of the gamma-aminobutyric acid type A receptor by [3H]flunitrazepam is histidine 102 of the alpha subunit.

21 January 2018

1 reference

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Photoaffinity labeling of the benzodiazepine binding site of alpha1beta3gamma2 gamma-aminobutyric acidA receptors with flunitrazepam identifies a subset of ligands that interact directly with His102 of the alpha subunit and predicts orientation of t

21 January 2018

1 reference

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Subtle changes in residue 77 of the gamma subunit of alpha1beta2gamma2 GABAA receptors drastically alter the affinity for ligands of the benzodiazepine binding site

21 January 2018

1 reference

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gamma-Aminobutyric acid type A receptor point mutation increases the affinity of compounds for the benzodiazepine site

21 January 2018

1 reference

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Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor

21 January 2018

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A point mutation in the gamma2 subunit of gamma-aminobutyric acid type A receptors results in altered benzodiazepine binding site specificity

21 January 2018

1 reference

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Gamma-aminobutyric acidA receptor alpha 5-subunit creates novel type II benzodiazepine receptor pharmacology.

21 January 2018

1 reference

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Development of stable cell lines expressing different subtypes of GABAA receptors

21 January 2018

1 reference

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Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

21 January 2018

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High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

1 reference

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Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor

21 January 2018

1 reference

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Pharmacological profile of benzodiazepine site ligands with recombinant GABAA receptor subtypes

21 January 2018

1 reference

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Amino acid residue 200 on the alpha1 subunit of GABA(A) receptors affects the interaction with selected benzodiazepine binding site ligands

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.19.13370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10224099%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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