Restoration of correct splicing of thalassemic beta-globin pre-mRNA by modified U1 snRNAs (Q74254054)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Restoration of correct splicing of thalassemic beta-globin pre-mRNA by modified U1 snRNAs (English)

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9 November 2019

author name string

Gorman L

series ordinal

1

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9 November 2019

Mercatante DR

series ordinal

2

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9 November 2019

Kole R

series ordinal

3

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9 November 2019

language of work or name

English

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publication date

1 November 2000

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Journal of Biological Chemistry

9 November 2019

published in

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9 November 2019

volume

275

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9 November 2019

page(s)

35914-35919

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9 November 2019

issue

46

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Molecular mechanisms of antisense drugs: RNase H.

9 November 2019

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Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides

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Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides

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Antisense oligonucleotides with different backbones. Modification of splicing pathways and efficacy of uptake

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21 January 2018

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U1 small nuclear RNAs with altered specificity can be stably expressed in mammalian cells and promote permanent changes in pre-mRNA splicing

21 January 2018

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A compensatory base change in U1 snRNA suppresses a 5' splice site mutation

21 January 2018

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21 January 2018

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Double-target antisense U7 snRNAs promote efficient skipping of an aberrant exon in three human beta-thalassemic mutations

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21 January 2018

Identifiers

DOI

10.1074/JBC.M006259200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10969081%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference