A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease. (Q48019594)

7 February 2018

title

A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease. (English)

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7 February 2018

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Yacyshyn BR

1

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7 February 2018

Bowen-Yacyshyn MB

2

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7 February 2018

Jewell L

3

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7 February 2018

Tami JA

4

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7 February 2018

Bennett CF

5

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7 February 2018

Kisner DL

6

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7 February 2018

Shanahan WR Jr

7

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7 February 2018

language of work or name

English

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publication date

1 June 1998

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7 February 2018

published in

Gastroenterology

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7 February 2018

volume

114

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7 February 2018

issue

6

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7 February 2018

page(s)

1133-1142

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7 February 2018

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

cites work

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7 January 2021

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Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

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Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells

7 January 2021

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Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence

7 January 2021

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CD54/intercellular adhesion molecule 1 and major histocompatibility complex II signaling induces B cells to express interleukin 2 receptors and complements help provided through CD40 ligation

7 January 2021

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Adhesion molecules and their role in inflammation

7 January 2021

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Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.

7 January 2021

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Expression of leukocyte adhesion molecules by mucosal mononuclear phagocytes in inflammatory bowel disease

7 January 2021

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Light and electron microscopic immunolocalization of endothelial leucocyte adhesion molecule-1 in inflammatory bowel disease. Morphological evidence of active synthesis and secretion into vascular lumen

7 January 2021

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Crohn's disease, ulcerative colitis, and normal intestinal lymphocytes express integrins in dissimilar patterns

7 January 2021

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Altered expression of alpha 4 beta 7, a gut homing integrin, by circulating and mucosal T cells in colonic mucosal inflammation

7 January 2021

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Cationic lipid is not required for uptake and selective inhibitory activity of ICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes

7 January 2021

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Oligodeoxynucleotide stability in subcellular extracts and culture media

7 January 2021

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Effects of phosphorothioate capping on antisense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

7 January 2021

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Enhanced metastatic ability of TNF-alpha-treated malignant melanoma cells is reduced by intercellular adhesion molecule-1 (ICAM-1, CD54) antisense oligonucleotides

7 January 2021

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Role of the intercellular adhesion molecule-1(ICAM-1) in endotoxin-induced pneumonia evaluated using ICAM-1 antisense oligonucleotides, anti-ICAM-1 monoclonal antibodies, and ICAM-1 mutant mice

7 January 2021

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Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a four-week study in cynomolgus monkeys.

7 January 2021

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7 January 2021

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Coronary endothelial and cardiac protective effects of a monoclonal antibody to intercellular adhesion molecule-1 in myocardial ischemia and reperfusion

7 January 2021

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Development and validation of an endoscopic index of the severity for Crohn's disease: a prospective multicentre study. Groupe d'Etudes Thérapeutiques des Affections Inflammatoires du Tube Digestif (GETAID)

7 January 2021

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Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Canadian Crohn's Relapse Prevention Trial Study Group

7 January 2021

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Quantitation of phosphorothioate oligonucleotides in human plasma

7 January 2021

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Functional evidence that intercellular adhesion molecule-1 (icam-1) is a ligand for lfa-1d-ependent adhesion in t cell-mediated cytotoxicity

7 January 2021

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Molecules and structures involved in the adhesion of natural killer cells to vascular endothelium

7 January 2021

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Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1

7 January 2021

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Regulation of endothelial cell adhesion molecule expression with antisense oligonucleotides

7 January 2021

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0016-5085(98)70418-4

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7 February 2018

PubMed ID

9609749

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7 February 2018