Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation (Q28586360)

31 January 2017

title

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation (English)

1 reference

31 January 2017

8

A. Ashworth

1 reference

31 January 2017

7

V. L. Tybulewicz

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9398843

28 November 2024

author name string

F. Connor

1

1 reference

31 January 2017

D. Bertwistle

2

1 reference

31 January 2017

P. J. Mee

3

1 reference

31 January 2017

G. M. Ross

4

1 reference

31 January 2017

S. Swift

5

1 reference

31 January 2017

E. Grigorieva

6

1 reference

31 January 2017

publication date

1 December 1997

1 reference

31 January 2017

December 1997

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9398843

http://www.nature.com/articles/ng1297-423

28 November 2024

language of work or name

English

0 references

work available at URL

1 reference

http://www.nature.com/articles/ng1297-423.pdf

28 November 2024

1 reference

28 November 2024

1 reference

31 January 2017

volume

17

1 reference

31 January 2017

issue

4

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31 January 2017

page(s)

423–430

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Association of BRCA1 with Rad51 in mitotic and meiotic cells

31 January 2017

cites work

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Internal repeats in the BRCA2 protein sequence

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The BRC repeats are conserved in mammalian BRCA2 proteins

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Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

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DNA repair: RAD alert

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The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

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Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

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Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

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A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes

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Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

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Breast and other cancers in families with ataxia-telangiectasia

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Heterozygous ATM mutations do not contribute to early onset of breast cancer

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Double indemnity: p53, BRCA and cancer. p53 mutation partially rescues developmental arrest in Brca1 and Brca2 null mice, suggesting a role for familial breast cancer genes in DNA damage repair

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Transcriptional activation by BRCA1

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Inherited breast and ovarian cancer.

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Linkage of early-onset familial breast cancer to chromosome 17q21

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7 January 2021

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

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7 January 2021

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

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7 January 2021

BRCA1 mutations in primary breast and ovarian carcinomas

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7 January 2021

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

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7 January 2021

Transcriptional activation functions in BRCA2

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Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

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7 January 2021

Brca2 is required for embryonic cellular proliferation in the mouse

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7 January 2021

Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

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7 January 2021

Wild-type p53 transgenic mice exhibit altered differentiation of the ureteric bud and possess small kidneys

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7 January 2021

Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

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7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

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7 January 2021

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7 January 2021

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7 January 2021

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