Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix (Q74036849)

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8 November 2019

title

Thermus aquaticus DNA polymerase I mutants with altered fidelity. Interacting mutations in the O-helix (English)

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8 November 2019

Thermus aquaticus

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Suzuki M

1

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8 November 2019

Yoshida S

2

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8 November 2019

Adman ET

3

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8 November 2019

Blank A

4

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8 November 2019

Loeb LA

5

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8 November 2019

language of work or name

English

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publication date

1 October 2000

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Journal of Biological Chemistry

8 November 2019

published in

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8 November 2019

volume

275

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8 November 2019

issue

42

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8 November 2019

page(s)

32728-32735

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Fidelity of DNA synthesis

8 November 2019

cites work

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Fidelity mechanisms in DNA replication

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Compilation, alignment, and phylogenetic relationships of DNA polymerases

21 January 2018

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Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

21 January 2018

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Crystal structure of Thermus aquaticus DNA polymerase

21 January 2018

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Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5-A resolution: structural basis for thermostability

21 January 2018

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Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

21 January 2018

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Structure-based design of Taq DNA polymerases with improved properties of dideoxynucleotide incorporation

21 January 2018

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Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal

21 January 2018

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

21 January 2018

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Function and structure relationships in DNA polymerases

21 January 2018

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A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides

21 January 2018

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How E. coli DNA polymerase I (Klenow fragment) distinguishes between deoxy- and dideoxynucleotides

21 January 2018

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A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity

21 January 2018

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Base miscoding and strand misalignment errors by mutator Klenow polymerases with amino acid substitutions at tyrosine 766 in the O helix of the fingers subdomain

21 January 2018

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Side chains that influence fidelity at the polymerase active site of Escherichia coli DNA polymerase I (Klenow fragment)

21 January 2018

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Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure

21 January 2018

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Low fidelity mutants in the O-helix of Thermus aquaticus DNA polymerase I.

21 January 2018

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Biochemical basis of DNA replication fidelity

21 January 2018

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Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA.

21 January 2018

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Analyzing fidelity of DNA polymerases.

21 January 2018

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Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR

21 January 2018

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Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

21 January 2018

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Elementary steps in the DNA polymerase I reaction pathway

21 January 2018

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Mechanism of the idling-turnover reaction of the large (Klenow) fragment of Escherichia coli DNA polymerase I.

21 January 2018

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Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant

21 January 2018

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Frameshift errors initiated by nucleotide misincorporation

21 January 2018

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Deoxynucleoside triphosphate and pyrophosphate binding sites in the catalytically competent ternary complex for the polymerase reaction catalyzed by DNA polymerase I (Klenow fragment).

21 January 2018

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The Protein Data Bank. A computer-based archival file for macromolecular structures

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

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Raster3D Version 2.0. A program for photorealistic molecular graphics

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21 January 2018

Identifiers

DOI

10.1074/JBC.M000097200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10906120%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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