Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNF-alpha, IL-3 withdrawal, and ionizing radiation (Q73580448)

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scientific article published on 01 June 2003

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English	Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNF-alpha, IL-3 withdrawal, and ionizing radiation	scientific article published on 01 June 2003

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scholarly article

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5 November 2019

Overexpression of the transgene for manganese superoxide dismutase (MnSOD) in 32D cl 3 cells prevents apoptosis induction by TNF-alpha, IL-3 withdrawal, and ionizing radiation (English)

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5 November 2019

Michael W Epperly

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object named as

Michael W Epperly

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5 November 2019

author name string

Michael Bernarding

2

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5 November 2019

Joan Gretton

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5 November 2019

Mia Jefferson

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5 November 2019

Suhua Nie

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5 November 2019

Joel S Greenberger

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publication date

1 June 2003

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5 November 2019

Experimental Hematology

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5 November 2019

31

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465-474

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5 November 2019

Increase in manganese superoxide dismutase activity in the mouse heart after X-irradiation

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Free radical-induced pathology

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DNA damage and repair following treatment with ionizing radiation

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p53, the cellular gatekeeper for growth and division

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p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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Bax-induced apoptotic cell death

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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Manganese superoxide dismutase (SOD2) inhibits radiation-induced apoptosis by stabilization of the mitochondrial membrane

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Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

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Caspases: enemies within

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Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria

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Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

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7 January 2021

based on heuristic

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Overexpression of the human manganese superoxide dismutase (MnSOD) transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest

1 reference

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Overexpression of mitochondrial manganese superoxide dismutase promotes the survival of tumor cells exposed to interleukin-1, tumor necrosis factor, selected anticancer drugs, and ionizing radiation.

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7 January 2021

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Protective roles of cytokines against radiation: induction of mitochondrial MnSOD.

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Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines

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Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

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Regulation of antioxidant enzymes in lung after oxidant injury

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Superoxide dismutase and pulmonary oxygen toxicity

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Superoxide radical and superoxide dismutases

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7 January 2021

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Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax

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7 January 2021

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tBID Homooligomerizes in the mitochondrial membrane to induce apoptosis

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7 January 2021

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Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

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Rapid kinetics of tBid-induced cytochrome c and Smac/DIABLO release and mitochondrial depolarization

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Mitochondrial respiratory control is lost during growth factor deprivation

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7 January 2021

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Bcl-2 and Bax function independently to regulate cell death

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Angiotensin type 2 receptor dephosphorylates Bcl-2 by activating mitogen-activated protein kinase phosphatase-1 and induces apoptosis

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Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

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Identification of a neuronal nitric oxide synthase in isolated cardiac mitochondria using electrochemical detection

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The catabolic fate of nitric oxide: the nitric oxide oxidase and peroxynitrite reductase activities of cytochrome oxidase

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Modulation of redox signal transduction pathways in the treatment of cancer

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Identification of respiratory complexes I and III as mitochondrial sites of damage following exposure to ionizing radiation and nitric oxide

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Metabolic oxidative stress activates signal transduction and gene expression during glucose deprivation in human tumor cells.

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Identifiers

10.1016/S0301-472X(03)00041-9

1 reference

Europe PubMed Central

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5 November 2019

1 reference

Europe PubMed Central

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5 November 2019

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