Interaction of thrombin with antithrombin, heparin cofactor II, and protein C inhibitor (Q72310830)

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25 October 2019

title

Interaction of thrombin with antithrombin, heparin cofactor II, and protein C inhibitor (English)

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25 October 2019

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H C Whinna

1

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25 October 2019

F C Church

series ordinal

2

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25 October 2019

publication date

1 December 1993

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25 October 2019

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25 October 2019

volume

12

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25 October 2019

issue

6

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25 October 2019

page(s)

677-688

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https://scigraph.springernature.com/pub.10.1007/bf01024926

25 October 2019

exact match

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cites work

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Rapid sulfopropyl-disk chromatographic purification of bovine and human thrombin

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The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Substitution of arginine for Leu444 in the reactive site of heparin cofactor II enhances the rate of thrombin inhibition

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A comparison of three heparin-binding serine proteinase inhibitors

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Rapid method for the purification of bovine thrombin and the inhibition of the purified enzyme with phenylmethylsulfonyl fluoride

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Human neutrophil elastase alters human alpha-thrombin function: limited proteolysis near the gamma-cleavage site results in decreased fibrinogen clotting and platelet-stimulatory activity

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Detection of a new heparin-dependent inhibitor of thrombin in human plasma

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Physicochemical aspects of heparin cofactor II.

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Heparin binding to protein C inhibitor

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12 December 2020

Protein C inhibitor: purification and proteinase reactivity

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Molecular and cellular biology of blood coagulation

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Antithrombin: structure and function

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Heparin-catalyzed inhibitor/protease reactions: kinetic evidence for a common mechanism of action of heparin

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Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition

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12 December 2020

Reactive site peptide structural similarity between heparin cofactor II and antithrombin III

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Identification of regions of alpha-thrombin involved in its interaction with hirudin

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Identification of the primary structural defect in the dysthrombin thrombin Quick I: substitution of cysteine for arginine-382

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Role of thrombin exosites in inhibition by heparin cofactor II

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Role of lysine 173 in heparin binding to heparin cofactor II.

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Interaction of human alpha-thrombin and gamma-thrombin with antithrombin III, protein C and thrombomodulin

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Protein C inhibitor: structure and function

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12 December 2020

Structural evidence for leucine at the reactive site of heparin cofactor II

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Leukocyte chemoattractant peptides from the serpin heparin cofactor II.

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Evidence for essential lysines in heparin cofactor II

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Localization of anticoagulantly active heparan sulfate proteoglycans in vascular endothelium: antithrombin binding on cultured endothelial cells and perfused rat aorta

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Substitution of valine for glycine-558 in the congenital dysthrombin thrombin Quick II alters primary substrate specificity

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Anion-binding exosite of human alpha-thrombin and fibrin(ogen) recognition

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Subtle differences in active site structure between bovine and human thrombins: ESR and fluorescence studies

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Inhibition of dysthrombins Quick I and II by heparin cofactor II and antithrombin.

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12 December 2020

Structure and biological activity of heparin.

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12 December 2020

Regulation of thrombin generation and functions

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12 December 2020

Characterization of a cDNA for human protein C inhibitor. A new member of the plasma serine protease inhibitor superfamily

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12 December 2020

Protein C inhibitor. Purification from human plasma and characterization

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12 December 2020

Refined structure of the hirudin-thrombin complex

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12 December 2020

The anticoagulant effect of heparan sulfate and dermatan sulfate

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12 December 2020

Thrombin structure and function: why thrombin is the primary target for antithrombotics

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12 December 2020

The protease specificity of heparin cofactor II. Inhibition of thrombin generated during coagulation.

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12 December 2020

Staphylocoagulase-binding region in human prothrombin

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12 December 2020

Structure-function relationships in human alpha- and gamma-thrombins

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12 December 2020

Transient kinetics of heparin-catalyzed protease inactivation by antithrombin III. Linkage of protease-inhibitor-heparin interactions in the reaction with thrombin.

1 reference

12 December 2020

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

1 reference

12 December 2020

The reaction of bovine alpha-thrombin with tetranitromethane. Characterization of the modified protein

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF01024926

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8136018%20AND%20SRC:MED&resulttype=core&format=json

25 October 2019

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