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Nuclear mitotic apparatus protein 1 (Q7068151)

From Wikidata
mammalian protein found in Homo sapiens
  • SP-H antigen
  • NMP-22
  • nuclear mitotic apparatus protein 1
  • structural nuclear protein
  • NUMA1
  • nuclear matrix protein-22
  • centrophilin stabilizes mitotic spindle in mitotic cells
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    English
    Nuclear mitotic apparatus protein 1
    mammalian protein found in Homo sapiens
    • SP-H antigen
    • NMP-22
    • nuclear mitotic apparatus protein 1
    • structural nuclear protein
    • NUMA1
    • nuclear matrix protein-22
    • centrophilin stabilizes mitotic spindle in mitotic cells

    Statements

    molecular function
    protein binding
    determination method or standard
    IPI
    17 references
    retrieved
    8 April 2019
    stated in
    NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A potential role for human cohesin in mitotic spindle aster assembly
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Rae1 interaction with NuMA is required for bipolar spindle formation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    A proteome-scale map of the human interactome network
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Rae1 interaction with NuMA is required for bipolar spindle formation
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
    GOA
    curator
    IntAct protein interaction database
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    retrieved
    8 April 2019
    stated in
    NMR characterisation of the minimal interacting regions of centrosomal proteins 4.1R and NuMA1: effect of phosphorylation
    GOA
    curator
    Critical Assessment of Protein Function Annotation
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IPI
    dynein complex binding
    determination method or standard
    IDA
    5 references
    retrieved
    8 April 2019
    stated in
    Rae1 interaction with NuMA is required for bipolar spindle formation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Cortical dynein is critical for proper spindle positioning in human cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Formation of spindle poles by dynein/dynactin-dependent transport of NuMA
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    cell component
    mitotic spindle astral microtubule
    determination method or standard
    IDA
    5 references
    retrieved
    8 April 2019
    stated in
    NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Polyglutamylated Tubulin Binding Protein C1orf96/CSAP Is Involved in Microtubule Stabilization in Mitotic Spindles
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Formation of spindle poles by dynein/dynactin-dependent transport of NuMA
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    mitotic spindle pole
    determination method or standard
    IDA
    IEA
    IMP
    17 references
    retrieved
    8 April 2019
    stated in
    Rae1 interaction with NuMA is required for bipolar spindle formation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Nuclear mitotic apparatus protein (NuMA): spindle association, nuclear targeting and differential subcellular localization of various NuMA isoforms
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    RanGTP and CLASP1 cooperate to position the mitotic spindle
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Formation of spindle poles by dynein/dynactin-dependent transport of NuMA
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    cell cortex region
    determination method or standard
    IDA
    IEA
    7 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    spindle pole
    determination method or standard
    IBA
    IDA
    IEA
    6 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    TOGp, the human homolog of XMAP215/Dis1, is required for centrosome integrity, spindle pole organization, and bipolar spindle assembly
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1
    GOA
    curator
    Mouse Genome Informatics
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IBA
    biological process
    establishment of mitotic spindle orientation
    determination method or standard
    IDA
    IEA
    IMP
    ISS
    5 references
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14980&geneProductId=UniProtKB:Q14980
    determination method or standard
    ISS
    retrieved
    31 October 2017
    stated in
    NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14980&geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    31 October 2017
    stated in
    NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures.
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14980&geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    31 October 2017
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14980&geneProductId=UniProtKB:Q14980
    determination method or standard
    IEA
    retrieved
    31 October 2017
    stated in
    LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14980&geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    regulation of mitotic spindle organization
    determination method or standard
    IDA
    IMP
    5 references
    retrieved
    8 April 2019
    stated in
    Rae1 interaction with NuMA is required for bipolar spindle formation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Cortical dynein is critical for proper spindle positioning in human cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    positive regulation of protein localization to cell cortex
    determination method or standard
    IMP
    6 references
    retrieved
    8 April 2019
    stated in
    NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Cortical dynein and asymmetric membrane elongation coordinately position the spindle in anaphase
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Cell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    NuMA phosphorylation by CDK1 couples mitotic progression with cortical dynein function
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    Cortical dynein is critical for proper spindle positioning in human cells
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    establishment of mitotic spindle orientation
    determination method or standard
    IBA
    IDA
    IEA
    IMP
    ISS
    6 references
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    ISS
    retrieved
    8 April 2019
    stated in
    NuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures.
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IMP
    retrieved
    8 April 2019
    stated in
    GOA
    curator
    Ensembl genome database project
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IEA
    retrieved
    8 April 2019
    stated in
    LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways
    GOA
    curator
    UniProt
    UniProt protein ID
    Q14980
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IDA
    retrieved
    8 April 2019
    stated in
    Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
    GOA
    curator
    GO Central
    reference URL
    http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14980
    determination method or standard
    IBA
    Gene Atlas image
    PBB GE NUMA1 200747 s at fs.png
    732 × 530; 12 KB
    0 references

    Identifiers

    RefSeq protein ID
    Ensembl protein ID
     
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                      Retrieved from "https://www.wikidata.org/w/index.php?title=Q7068151&oldid=2022909421"