Cortical dynein is critical for proper spindle positioning in human cells (Q24300064)

G protein signaling modulator 2

1 reference

Nuclear mitotic apparatus protein 1

1 reference

Dynein cytoplasmic 1 heavy chain 1

1 reference

Dynactin subunit 1

1 reference

positive regulation of protein localization to cell cortex

1 reference

Dynein heavy chain, cytoplasmic CELE_T21E12.4

1 reference

describes a project that uses

3

Pierre Gönczy

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Sachin Kotak

series ordinal

1

object named as

Sachin Kotak

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author name string

Sachin Kotak

series ordinal

1

0 references

Coralie Busso

series ordinal

2

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language of work or name

English

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publication date

1 October 2012

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number of pages

14

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based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

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volume

199

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page(s)

97-110

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issue

1

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ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3461507/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Rae1 interaction with NuMA is required for bipolar spindle formation

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19 March 2017

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1 reference

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Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis

19 March 2017

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Directed Evolution Reveals the Binding Motif Preference of the LC8/DYNLL Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome

19 March 2017

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Cell cycle-dependent microtubule-based dynamic transport of cytoplasmic dynein in mammalian cells

19 March 2017

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Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules

19 March 2017

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19 March 2017

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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

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7 April 2017

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Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation

7 April 2017

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Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein

10 May 2017

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Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters

27 September 2017

1 reference

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ABL1 regulates spindle orientation in adherent cells and mammalian skin.

27 September 2017

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Polarity mediates asymmetric trafficking of the Gbeta heterotrimeric G-protein subunit GPB-1 in C. elegans embryos

27 September 2017

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A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells

27 September 2017

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Asymmetric cell divisions promote Notch-dependent epidermal differentiation

27 September 2017

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Intracellular organelles mediate cytoplasmic pulling force for centrosome centration in the Caenorhabditis elegans early embryo

27 September 2017

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Ric-8A and Gi alpha recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle

27 September 2017

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LGN regulates mitotic spindle orientation during epithelial morphogenesis

27 September 2017

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27 September 2017

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Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos

27 September 2017

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Spindle orientation during asymmetric cell division

27 September 2017

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How does a millimeter-sized cell find its center?

27 September 2017

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A casein kinase 1 and PAR proteins regulate asymmetry of a PIP(2) synthesis enzyme for asymmetric spindle positioning

27 September 2017

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27 September 2017

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27 September 2017

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Dynamic localization of LIN-5 and GPR-1/2 to cortical force generation domains during spindle positioning

27 September 2017

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Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans

27 September 2017

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Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner

27 September 2017

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The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division

27 September 2017

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RIC-8 is required for GPR-1/2-dependent Galpha function during asymmetric division of C. elegans embryos

27 September 2017

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Return of the GDI: the GoLoco motif in cell division.

27 September 2017

1 reference

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Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function inC. elegans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

Calcium/calmodulin-dependent protein kinase II regulates Caenorhabditis elegans locomotion in concert with a G(o)/G(q) signaling network.

27 September 2017

1 reference

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The respective contributions of the mother and daughter centrioles to centrosome activity and behavior in vertebrate cells

27 September 2017

1 reference

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Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

Epitope mapping and direct visualization of the parallel, in-register arrangement of the double-stranded coiled-coil in the NuMA protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

NuMA: a bipartite nuclear location signal and other functional properties of the tail domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

Self assembly of NuMA: multiarm oligomers as structural units of a nuclear lattice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461507

Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryos.

30 May 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201203166

Participation of the protein Go in multiple aspects of behavior in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201203166

Coupling of cortical dynein and G alpha proteins mediates spindle positioning in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201203166

Codon adaptation–based control of protein expression in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201203166

The extracellular matrix guides the orientation of the cell division axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201203166

PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201203166

LET-99 opposes Galpha/GPR signaling to generate asymmetry for spindle positioning in response to PAR and MES-1/SRC-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201203166

21 January 2018

Identifiers

DOI

10.1083/JCB.201203166

1 reference

3115077

3115077

1 reference

1 reference

1 reference