Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT (Q64462274)

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9 January 2020

title

Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT (English)

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1

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Federico Pelisch

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Jorge P. Muschietti

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Alberto Kornblihtt

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Javier Caceres

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Anabella Srebrow

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author name string

Tamara Tanos

3

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Manuel J Muñoz

4

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Diego Wengier

5

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Leandro Quadrana

6

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Jeremy R Sanford

7

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Omar A Coso

11

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publication date

20 November 2005

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Nature Structural & Molecular Biology

9 January 2020

published in

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volume

12

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issue

12

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page(s)

1037-1044

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https://scigraph.springernature.com/pub.10.1038/nsmb1020

9 January 2020

exact match

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cites work

Alternative splicing: increasing diversity in the proteomic world

1 reference

Sorting out the complexity of SR protein functions

31 March 2020

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Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly

31 March 2020

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Determinants of SR protein specificity.

31 March 2020

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Identification of a bidirectional splicing enhancer: differential involvement of SR proteins in 5' or 3' splice site activation

31 March 2020

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Pre-mRNA splicing in the new millennium

31 March 2020

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Associations between distinct pre-mRNA splicing components and the cell nucleus

31 March 2020

1 reference

Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity

31 March 2020

1 reference

Transportin-SR2 mediates nuclear import of phosphorylated SR proteins

31 March 2020

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A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm

31 March 2020

1 reference

SRprises along a messenger's journey

31 March 2020

1 reference

Stability of a PKCI-1-related mRNA is controlled by the splicing factor ASF/SF2: a novel function for SR proteins

31 March 2020

1 reference

Involvement of SR proteins in mRNA surveillance

31 March 2020

1 reference

A novel role for shuttling SR proteins in mRNA translation

31 March 2020

1 reference

Cell signalling and the control of pre-mRNA splicing.

31 March 2020

1 reference

Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells

31 March 2020

1 reference

The MKK(3/6)-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation

31 March 2020

1 reference

Protein kinase A phosphorylation modulates transport of the polypyrimidine tract-binding protein

31 March 2020

1 reference

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

31 March 2020

1 reference

Specific phosphorylation of SR proteins by mammalian DNA topoisomerase I.

31 March 2020

1 reference

The fibronectin gene as a model for splicing and transcription studies.

31 March 2020

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Alternatively spliced EDA segment regulates fibronectin-dependent cell cycle progression and mitogenic signal transduction

31 March 2020

1 reference

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan

31 March 2020

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A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon

31 March 2020

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A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding

31 March 2020

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Mammary epithelial-mesenchymal interaction regulates fibronectin alternative splicing via phosphatidylinositol 3-kinase.

31 March 2020

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The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.

31 March 2020

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Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

31 March 2020

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RNA folding affects the recruitment of SR proteins by mouse and human polypurinic enhancer elements in the fibronectin EDA exon

31 March 2020

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Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer

31 March 2020

1 reference

Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles

31 March 2020

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4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

31 March 2020

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SR proteins Asf/SF2 and 9G8 interact to activate enhancer-dependent intron D splicing of bovine growth hormone pre-mRNA in vitro

31 March 2020

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Cross-talk between signaling pathways regulates alternative splicing: a novel role for JNK.

31 March 2020

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Signal-dependent regulation of splicing via phosphorylation of Sam68

31 March 2020

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Molecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40

31 March 2020

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HRS/SRp40-mediated inclusion of the fibronectin EIIIB exon, a possible cause of increased EIIIB expression in proliferating liver

31 March 2020

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The Glc7p nuclear phosphatase promotes mRNA export by facilitating association of Mex67p with mRNA

31 March 2020

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Reversible phosphorylation differentially affects nuclear and cytoplasmic functions of splicing factor 2/alternative splicing factor.

31 March 2020

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The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing

31 March 2020

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The splicing factors 9G8 and SRp20 transactivate splicing through different and specific enhancers.

31 March 2020

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Activation of JNK by Epac is independent of its activity as a Rap guanine nucleotide exchanger

31 March 2020

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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

31 March 2020

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Stress-induced nuclear bodies are sites of accumulation of pre-mRNA processing factors

31 March 2020

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The Clk2 and Clk3 dual-specificity protein kinases regulate the intranuclear distribution of SR proteins and influence pre-mRNA splicing

31 March 2020

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A slow RNA polymerase II affects alternative splicing in vivo

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB1020

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9 January 2020

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