Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan (Q28593378)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12847088%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Regulated splicing of the fibronectin EDA exon is essential for proper skin wound healing and normal lifespan (English)

2 references

31 January 2017

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5 November 2019

1 reference

GOA release 2020-03-11

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1 reference

1

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5 November 2019

Anil K Chauhan

2

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5 November 2019

Srecko Gajovic

3

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5 November 2019

Giorgio Stanta

6

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5 November 2019

author name string

Alessandra Iaconcig

4

2 references

31 January 2017

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5 November 2019

Fabiola Porro

5

2 references

31 January 2017

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5 November 2019

Francisco E Baralle

7

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5 November 2019

language of work or name

English

0 references

publication date

1 July 2003

1 reference

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5 November 2019

number of pages

12

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inferred from page(s)

published in

Journal of Cell Biology

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31 January 2017

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5 November 2019

volume

162

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5 November 2019

issue

1

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31 January 2017

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5 November 2019

page(s)

149-160

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12847088%20AND%20SRC:MED&resulttype=core&format=json

Distinct functions of the two isoforms of dopamine D2 receptors

5 November 2019

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The extra domain A of fibronectin activates Toll-like receptor 4.

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Normal electrophysiological and behavioral responses to ethanol in mice lacking the long splice variant of the gamma2 subunit of the gamma-aminobutyrate type A receptor.

29 September 2017

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Regulation of fibronectin EDA exon alternative splicing: possible role of RNA secondary structure for enhancer display.

29 September 2017

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Cre-loxP-mediated inactivation of the alpha6A integrin splice variant in vivo: evidence for a specific functional role of alpha6A in lymphocyte migration but not in heart development.

29 September 2017

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Alternative splicing of the fibronectin EIIIB exon depends on specific TGCATG repeats

29 September 2017

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Modulation of cell-adhesive activity of fibronectin by the alternatively spliced EDA segment

29 September 2017

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The fibronectin gene as a model for splicing and transcription studies.

29 September 2017

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A novel bipartite splicing enhancer modulates the differential processing of the human fibronectin EDA exon

29 September 2017

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Alternative splicing of fibronectin--many different proteins but few different functions

29 September 2017

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Plasma fibronectin is synthesized and secreted by hepatocytes

29 September 2017

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Three different fibronectin mRNAs arise by alternative splicing within the coding region

29 September 2017

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29 September 2017

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A role for exon sequences in alternative splicing of the human fibronectin gene

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Identification of a third region of cell-specific alternative splicing in human fibronectin mRNA

29 September 2017

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Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat.

29 September 2017

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Selective secretion of alternatively spliced fibronectin variants

29 September 2017

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29 September 2017

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Multiple sites of alternative splicing of the rat fibronectin gene transcript

29 September 2017

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29 September 2017

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29 September 2017

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Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos

29 September 2017

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29 September 2017

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Regulation of CS1 fibronectin expression and function by IL-1 in endothelial cells

29 September 2017

1 reference

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Regulation of the fibronectin EDA exon alternative splicing. Cooperative role of the exonic enhancer element and the 5' splicing site

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172721

Adhesion activity in fibronectin's alternatively spliced domain EDa (EIIIA): complementarity to plasma fibronectin functions

3 June 2018

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Transformed human cells produce a new fibronectin isoform by preferential alternative splicing of a previously unobserved exon

3 June 2018

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Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo

3 June 2018

1 reference

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Polarized regulation of fibronectin secretion and alternative splicing by transforming growth factor

3 June 2018

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The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172721

The EIIIA segment of fibronectin is a ligand for integrins alpha 9beta 1 and alpha 4beta 1 providing a novel mechanism for regulating cell adhesion by alternative splicing.

3 June 2018

1 reference

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Lysosomal acid lipase-deficient mice: depletion of white and brown fat, severe hepatosplenomegaly, and shortened life span.

27 November 2018

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Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis.

27 November 2018

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A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding

27 November 2018

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12 December 2020

Analysis of the linkage between fibronectin alternative spliced sites during ageing in rat tissues

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12 December 2020

Mesodermal development in mouse embryos mutant for fibronectin

1 reference

12 December 2020

Alternatively spliced EDA segment regulates fibronectin-dependent cell cycle progression and mitogenic signal transduction

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12 December 2020

Different responses to surgical stress between extra domain A+ and plasma fibronectins

1 reference

12 December 2020

Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock

1 reference

12 December 2020

Mice lacking the EDB segment of fibronectin develop normally but exhibit reduced cell growth and fibronectin matrix assembly in vitro

1 reference

12 December 2020

Lifespan and incidence of cancer and other diseases in selected long-lived inbred mice and their F 1 hybrids

1 reference

12 December 2020

Life-Span and the Inheritance of Longevity of Inbred Mice

1 reference

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Fibronectin and fibrin provide a provisional matrix for epidermal cell migration during wound reepithelialization

1 reference

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Fibronectin Beneath Reepithelializing Epidermis in Vivo: Sources and Significance

1 reference

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Patterns of alternative splicing of fibronectin pre-mRNA in human adult and fetal tissues

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12 December 2020

Identifiers

DOI

10.1083/JCB.200212079

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12847088%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12847088%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

2 references