Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway (Q60301842)

2

0 references

Zhonglin Zhang

3

0 references

Chao Ma

4

0 references

Tingting Wu

5

0 references

Shengli Tang

6

0 references

Zongyue Zeng

7

0 references

Shifeng Huang

8

0 references

Cheng Gong

9

0 references

Chengfu Yuan

10

0 references

Linghuan Zhang

11

0 references

Yixiao Feng

12

0 references

Bo Huang

13

0 references

Wei Liu

14

0 references

Bo Zhang

15

0 references

Yi Shen

16

0 references

Wenping Luo

17

0 references

Xi Wang

18

0 references

Bo Liu

19

0 references

Yan Lei

20

0 references

Zhenyu Ye

21

0 references

Ling Zhao

22

0 references

Daigui Cao

23

0 references

Lijuan Yang

24

0 references

Xian Chen

25

0 references

Rex C Haydon

26

0 references

Hue H Luu

27

0 references

Bing Peng

28

0 references

Xubao Liu

29

0 references

Tong-Chuan He

Creative Commons Attribution 4.0 International

30

0 references

language of work or name

English

0 references

publication date

17 December 2018

0 references

published in

Scientific Reports

0 references

volume

8

0 references

page(s)

17914

0 references

issue

1

0 references

copyright license

start time

1 December 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Recent progress in pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Pancreatic cancer stromal biology and therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Cancer statistics, 2018.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

1 reference

7 January 2021

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

1 reference

7 January 2021

Epidemiology of pancreatic cancer: an overview

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Cancer statistics in China, 2015.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Gemcitabine resistance in pancreatic ductal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Genomic analyses identify molecular subtypes of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Molecular alterations contributing to pancreatic cancer chemoresistance

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Drug repurposing in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Repurposing Drugs in Oncology: Next Steps

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Cancer drug discovery by repurposing: teaching new tricks to old dogs

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

An Insight into Drug Repositioning for the Development of Novel Anti-Cancer Drugs

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Monensin inhibits epidermal growth factor receptor trafficking and activation: synergistic cytotoxicity in combination with EGFR inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Conditionally immortalized mouse embryonic fibroblasts retain proliferative activity without compromising multipotent differentiation potential

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability While Retaining Chondrogenic Phenotype

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Sox9 augments BMP2-induced chondrogenic differentiation by downregulating Smad7 in mesenchymal stem cells (MSCs).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Establishment and characterization of a new highly metastatic human osteosarcoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

BMP9 induces osteogenesis and adipogenesis in the immortalized human cranial suture progenitors from the patent sutures of craniosynostosis patients.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Sustained high level transgene expression in mammalian cells mediated by the optimized piggyBac transposon system

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Establishment and characterization of the reversibly immortalized mouse fetal heart progenitors

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Targeting BMP9-promoted human osteosarcoma growth by inactivation of notch signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Lysophosphatidic acid acyltransferase β (LPAATβ) promotes the tumor growth of human osteosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Increased expression of S100A6 is associated with decreased metastasis and inhibition of cell migration and anchorage independent growth in human osteosarcoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

IGFBP5 domains exert distinct inhibitory effects on the tumorigenicity and metastasis of human osteosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

The Calcium-Binding Protein S100A6 Accelerates Human Osteosarcoma Growth by Promoting Cell Proliferation and Inhibiting Osteogenic Differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Functional characteristics of reversibly immortalized hepatic progenitor cells derived from mouse embryonic liver.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Characterization of constitutive promoters for piggyBac transposon-mediated stable transgene expression in mesenchymal stem cells (MSCs).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

TGFbeta/BMP type I receptors ALK1 and ALK2 are essential for BMP9-induced osteogenic signaling in mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Synergistic antitumor effect of the activated PPARgamma and retinoid receptors on human osteosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Tetrandrine inhibits Wnt/β-catenin signaling and suppresses tumor growth of human colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Conditional immortalization establishes a repertoire of mouse melanocyte progenitors with distinct melanogenic differentiation potential

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Drug combination studies and their synergy quantification using the Chou-Talalay method

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

A thermoresponsive polydiolcitrate-gelatin scaffold and delivery system mediates effective bone formation from BMP9-transduced mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Gelatin-Derived Graphene-Silicate Hybrid Materials Are Biocompatible and Synergistically Promote BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Primer3--new capabilities and interfaces

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

TqPCR: A Touchdown qPCR Assay with Significantly Improved Detection Sensitivity and Amplification Efficiency of SYBR Green qPCR.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Characterization of retroviral infectivity and superinfection resistance during retrovirus-mediated transduction of mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Adenovirus-mediated efficient gene transfer into cultured three-dimensional organoids

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

The piggyBac transposon-mediated expression of SV40 T antigen efficiently immortalizes mouse embryonic fibroblasts (MEFs).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

S100A6 expression and function in human osteosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Niclosamide Exhibits Potent Anticancer Activity and Synergizes with Sorafenib in Human Renal Cell Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

CRISPR/Cas9-mediated reversibly immortalized mouse bone marrow stromal stem cells (BMSCs) retain multipotent features of mesenchymal stem cells (MSCs).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

NEL-Like Molecule-1 (Nell1) Is Regulated by Bone Morphogenetic Protein 9 (BMP9) and Potentiates BMP9-Induced Osteogenic Differentiation at the Expense of Adipogenesis in Mesenchymal Stem Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs).

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Monensin is a potent inducer of oxidative stress and inhibitor of androgen signaling leading to apoptosis in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Autophagy Inhibition with Monensin Enhances Cell Cycle Arrest and Apoptosis Induced by mTOR or Epidermal Growth Factor Receptor Inhibitors in Lung Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Monensin-mediated growth inhibition in acute myelogenous leukemia cells via cell cycle arrest and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Monensin-mediated growth inhibition in human lymphoma cells through cell cycle arrest and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Monensin inhibits canonical Wnt signaling in human colorectal cancer cells and suppresses tumor growth in multiple intestinal neoplasia mice

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Aberrant trafficking of NSCLC-associated EGFR mutants through the endocytic recycling pathway promotes interaction with Src.

1 reference

https://api.crossref.org/works/10.1038%2FS41598-018-36214-5

7 January 2021

Ionophorous antibiotics as models for biological transport

1 reference

12 December 2020

Monensin-mediated growth inhibition of SNU-C1 colon cancer cells via cell cycle arrest and apoptosis.

1 reference

12 December 2020

Monensin inhibits the growth of renal cell carcinoma cells via cell cycle arrest or apoptosis

1 reference

12 December 2020

Monensin-mediated growth inhibition in NCI-H929 myeloma cells via cell cycle arrest and apoptosis

1 reference

12 December 2020

Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells

1 reference

12 December 2020

Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration

1 reference

12 December 2020

Bone morphogenetic protein 9 (BMP9) induces effective bone formation from reversibly immortalized multipotent adipose-derived (iMAD) mesenchymal stem cells

1 reference

12 December 2020