Molecular analysis of the INK4A and INK4B gene loci in human breast cancer cell lines and primary carcinomas (Q59722436)

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7 November 2019

title

Molecular analysis of the INK4A and INK4B gene loci in human breast cancer cell lines and primary carcinomas (English)

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7 November 2019

4

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7 November 2019

Kimberly Van Zee

7

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7 November 2019

author name string

M Bisogna

1

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7 November 2019

J E Calvano

2

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7 November 2019

G H Ho

3

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7 November 2019

C Cordón-Cardó

5

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7 November 2019

P I Borgen

6

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7 November 2019

publication date

1 March 2001

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Cancer Genetics and Cytogenetics

7 November 2019

published in

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7 November 2019

volume

125

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7 November 2019

issue

2

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7 November 2019

page(s)

131-138

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Mutational analysis of the CDKN2 gene in metastases from patients with cutaneous malignant melanoma

7 November 2019

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The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

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Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

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Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

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Role of the INK4a locus in tumor suppression and cell mortality.

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P16 gene in uncultured tumours

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Analysis of MTS1/CDK4 in female breast carcinomas

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Absence of p16 gene (CDKN2) deletions in microdissected primary breast carcinoma specimens.

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Expression of the cyclin‐dependent kinase inhibitors p16INK4, p15INK4B and p21Waf1/cip1 in human breast cancer

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5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

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7 January 2021

Hypomethylation and increased gene expression of p16INK4a in primary and metastatic breast carcinoma as compared to normal breast tissue

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Splicing into senescence: the curious case of p16 and p19ARF.

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Deletion of the p16 and p15 Genes in Human Bladder Tumors

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Methylation of the multi tumor suppressor gene-2 (MTS2, CDKN1, p15INK4B) in childhood acute lymphoblastic leukemia

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p16INK4andp15INK4BAlterations in Primary Gynecologic Malignancy

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7 January 2021

Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

Alterations of INK4A and INK4B genes in adult soft tissue sarcomas: effect on survival

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7 January 2021

Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms

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7 January 2021

Design and testing of beta-actin primers for RT-PCR that do not co-amplify processed pseudogenes.

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Mutational analysis of the p15 and p16 genes in acute leukaemias

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7 January 2021

Alterations of p16INK4A and p15INK4B genes in gastric carcinomas

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7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

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7 January 2021

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Identifiers

DOI

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7 November 2019

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