Cooperative genetic changes in pediatric B-cell precursor acute lymphoblastic leukemia with deletions or mutations ofIKZF1 (Q59529214)

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1 March 2020

title

Cooperative genetic changes in pediatric B-cell precursor acute lymphoblastic leukemia with deletions or mutations of IKZF1 (English)

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1 March 2020

main subject

lymphoblastic leukemia

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6

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author name string

Linda Olsson

1

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1 March 2020

Ferras Albitar

2

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1 March 2020

Anders Castor

3

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1 March 2020

Mikael Behrendtz

4

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1 March 2020

Andrea Biloglav

5

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Bertil Johansson

7

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publication date

26 February 2015

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Genes, Chromosomes and Cancer

1 March 2020

published in

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volume

54

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page(s)

315-325

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issue

5

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FLT3 mutations in a 10 year consecutive series of 177 childhood acute leukemias and their impact on global gene expression patterns

1 March 2020

cites work

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7 January 2021

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

1 reference

7 January 2021

Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia.

1 reference

7 January 2021

Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study

1 reference

7 January 2021

An intragenic ERG deletion is a marker of an oncogenic subtype of B-cell precursor acute lymphoblastic leukemia with a favorable outcome despite frequent IKZF1 deletions.

1 reference

7 January 2021

Control of lymphocyte development by the Ikaros gene family

1 reference

7 January 2021

A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

1 reference

7 January 2021

IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

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7 January 2021

Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations.

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7 January 2021

Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment

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7 January 2021

The Ikaros gene is required for the development of all lymphoid lineages

1 reference

7 January 2021

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome

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7 January 2021

Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.

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7 January 2021

IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.

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7 January 2021

Fast and accurate short read alignment with Burrows-Wheeler transform

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7 January 2021

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project

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7 January 2021

Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles

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7 January 2021

IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report

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7 January 2021

A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia.

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7 January 2021

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

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7 January 2021

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

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7 January 2021

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

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7 January 2021

JAK mutations in high-risk childhood acute lymphoblastic leukemia

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7 January 2021

Impact of IKZF1 deletions and PAX5 amplifications in pediatric B-cell precursor ALL treated according to NOPHO protocols

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7 January 2021

Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.

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7 January 2021

What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

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7 January 2021

Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor

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7 January 2021

Ikaros isoform x is selectively expressed in myeloid differentiation.

1 reference

7 January 2021

Genetic loss of SH2B3 in acute lymphoblastic leukemia

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7 January 2021

Biology, risk stratification, and therapy of pediatric acute leukemias: an update

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7 January 2021

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia

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7 January 2021

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

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7 January 2021

Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia.

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7 January 2021

Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia

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7 January 2021

Infrequent occurrence of mutations in the PH domain of LNK in patients with JAK2 mutation-negative 'idiopathic' erythrocytosis

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7 January 2021

Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.

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7 January 2021

Location and function of linker histones

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7 January 2021

Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia

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7 January 2021

Tyrosine kinase inhibitor therapy induces remission in a patient with refractory EBF1-PDGFRB-positive acute lymphoblastic leukemia.

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7 January 2021

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

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7 January 2021

IKZF1 and CRLF2 gene alterations correlate with poor prognosis in Japanese BCR-ABL1-negative high-risk B-cell precursor acute lymphoblastic leukemia.

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7 January 2021

IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan

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7 January 2021

ERG deletion is associated with CD2 and attenuates the negative impact of IKZF1 deletion in childhood acute lymphoblastic leukemia.

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7 January 2021

Identifiers

DOI

10.1002/GCC.22245

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1 March 2020

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