Mapping catalytic promiscuity in the alkaline phosphatase superfamily (Q59504494)

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Language	Label	Description	Also known as
English	Mapping catalytic promiscuity in the alkaline phosphatase superfamily	No description defined

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instance of

scholarly article

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title

Mapping catalytic promiscuity in the alkaline phosphatase superfamily (English)

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Stefanie Jonas

1

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Florian Hollfelder

object named as

Florian Hollfelder

series ordinal

2

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publication date

1 January 2009

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published in

Pure and Applied Chemistry

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volume

81

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page(s)

731-742

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issue

4

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cites work

A superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatases

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Degrees of difficulty of water-consuming reactions in the absence of enzymes

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Rate-determining step of Escherichia coli alkaline phosphatase altered by the removal of a positive charge at the active center

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Amino acid residues forming the active site of arylsulfatase A. Role in catalytic activity and substrate binding

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Arginine Coordination in Enzymatic Phosphoryl Transfer: Evaluation of the Effect of Arg166 Mutations in Escherichia coli Alkaline Phosphatase † ‡

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Efficient Phosphodiester Binding and Cleavage by a ZnII Complex Combining Hydrogen-Bonding Interactions and Double Lewis Acid Activation

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Hydrolysis of phosphodiesters through transformation of the bacterial phosphotriesterase.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Evolutionary potential of (beta/alpha)8-barrels: in vitro enhancement of a "new" reaction in the enolase superfamily

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Binuclear Metallohydrolases

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Metal Activation of Enzymes in Nucleic Acid Biochemistry

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

1.3 A structure of arylsulfatase from Pseudomonas aeruginosa establishes the catalytic mechanism of sulfate ester cleavage in the sulfatase family

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Structure and mechanism of action of a novel phosphoglycerate mutase from Bacillus stearothermophilus

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

A general two-metal-ion mechanism for catalytic RNA

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

A revised mechanism for the alkaline phosphatase reaction involving three metal ions

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Reaction mechanism of alkaline phosphatase based on crystal structures. Two-metal ion catalysis

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Synthetic metallonucleases for RNA cleavage

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Structure and Nuclease Activity of Simple Dinuclear Metal Complexes: Quantitative Dissection of the Role of Metal Ions

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

De novo computational design of retro-aldol enzymes

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20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

CATH--a hierarchic classification of protein domain structures

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

The depth of chemical time and the power of enzymes as catalysts.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

The iron sulfur protein AtsB is required for posttranslational formation of formylglycine in the Klebsiella sulfatase.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Functional interrelationships in the alkaline phosphatase superfamily: phosphodiesterase activity of Escherichia coli alkaline phosphatase

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

SCOP: a structural classification of proteins database for the investigation of sequences and structures

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Models for biological phosphoryl transfer

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

A study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Identification, characterization, and cloning of a phosphonate monoester hydrolase from Burkholderia caryophilli PG2982.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Crystal structure of human arylsulfatase A: the aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

PROTEIN FAMILIES AND THEIR EVOLUTION—A STRUCTURAL PERSPECTIVE

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

The thermodynamics of phosphate versus phosphorothioate ester hydrolysis

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Enzyme recruitment in evolution of new function

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Dendrimers as artificial enzymes

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Alkaline phosphatase mono- and diesterase reactions: comparative transition state analysis

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

The 'evolvability' of promiscuous protein functions

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Alkaline phosphatase revisited: hydrolysis of alkyl phosphates

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Structure of a human lysosomal sulfatase

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal Ion

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

The nature of the transition state for enzyme-catalyzed phosphoryl transfer. Hydrolysis of O-aryl phosphorothioates by alkaline phosphatase

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

A gold standard set of mechanistically diverse enzyme superfamilies

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Probing the origin of the compromised catalysis of E. coli alkaline phosphatase in its promiscuous sulfatase reaction

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Kinetic isotope effects for alkaline phosphatase reactions: implications for the role of active-site metal ions in catalysis

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Robustness-epistasis link shapes the fitness landscape of a randomly drifting protein.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Structure and mechanism of alkaline phosphatase

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Directed evolution of the promiscuous esterase activity of carbonic anhydrase II.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Trapping the tetrahedral intermediate in the alkaline phosphatase reaction by substitution of the active site serine with threonine

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Mechanism and Catalytic Promiscuity: Emerging Mechanistic Principles for Identification and Manipulation of Catalytically Promiscuous Enzymes

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Evolutionary potential of (beta/alpha)8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Catalytic promiscuity in biocatalysis: using old enzymes to form new bonds and follow new pathways.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Enzyme promiscuity: evolutionary and mechanistic aspects.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Evolution of enzyme superfamilies

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

The mechanism of the alkaline phosphatase reaction: insights from NMR, crystallography and site-specific mutagenesis

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural studies of the 1,3-dichloropropene catabolic enzymes

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Catalytic promiscuity and the evolution of new enzymatic activities

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Ohno's model revisited: measuring the frequency of potentially adaptive mutations under various mutational drifts

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

A new member of the alkaline phosphatase superfamily with a formylglycine nucleophile: structural and kinetic characterisation of a phosphonate monoester hydrolase/phosphodiesterase from Rhizobium leguminosarum

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Efficient catalytic promiscuity in an enzyme superfamily: an arylsulfatase shows a rate acceleration of 10(13) for phosphate monoester hydrolysis

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Relation between structure and function of alpha/beta-proteins

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

The SUPERFAMILY database in 2007: families and functions

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Sulfatases, trapping of the sulfated enzyme intermediate by substituting the active site formylglycine

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Kemp elimination catalysts by computational enzyme design

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Alkaline phosphatase catalysis is ultrasensitive to charge sequestered between the active site zinc ions

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Directed evolution of phosphotriesterase from Pseudomonas diminuta for heterologous expression in Escherichia coli results in stabilization of the metal-free state.

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Catalysis by metal-activated hydroxide in zinc and manganese metalloenzymes

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

Multicopy suppression underpins metabolic evolvability

1 reference

20 August 2023

https://opencitations.net/index/coci/api/v1/references/10.1351/PAC-CON-08-10-20

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10.1351/PAC-CON-08-10-20

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Mapping catalytic promiscuity in the alkaline phosphatase superfamily (Q59504494)

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Mapping catalytic promiscuity in the alkaline phosphatase superfamily (Q59504494)

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