De novo computational design of retro-aldol enzymes (Q24609401)

5

Daniela Röthlisberger

0 references

David Baker

David Baker

14

0 references

Carlos Barbas

10

Carlos F Barbas

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Kendall Houk

12

Kendall N Houk

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author name string

Lin Jiang

1

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Eric A Althoff

2

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Fernando R Clemente

3

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Lindsey Doyle

4

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Daniela Röthlisberger

5

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Alexandre Zanghellini

6

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Jasmine L Gallaher

7

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Jamie L Betker

8

0 references

Donald Hilvert

11

0 references

Barry L Stoddard

Mechanism of the Class I KDPG aldolase

13

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language of work or name

English

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publication date

7 March 2008

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published in

Science

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volume

319

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page(s)

1387-91

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issue

5868

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431203

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

7 April 2017

1 reference

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

7 April 2017

1 reference

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Observation of covalent intermediates in an enzyme mechanism at atomic resolution

7 April 2017

1 reference

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The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data

7 April 2017

1 reference

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Selection and evolution of enzymes from a partially randomized non-catalytic scaffold

7 April 2017

1 reference

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Enzyme promiscuity: evolutionary and mechanistic aspects.

27 September 2017

1 reference

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Bacterial degradation of xenobiotic compounds: evolution and distribution of novel enzyme activities

27 September 2017

1 reference

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De novo design of catalytic proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431203

Evolution of aldolase antibodies in vitro: correlation of catalytic activity and reaction-based selection

27 September 2017

1 reference

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A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins

27 September 2017

1 reference

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Computational design of receptor and sensor proteins with novel functions

27 September 2017

1 reference

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Industrial enzyme applications

27 September 2017

1 reference

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A modular assembly strategy for improving the substrate specificity of small catalytic peptides

27 September 2017

1 reference

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Enzyme-like proteins by computational design

27 September 2017

1 reference

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Critical analysis of antibody catalysis.

27 September 2017

1 reference

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Directed evolution of biocatalysts

27 September 2017

1 reference

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Efficient aldolase catalytic antibodies that use the enamine mechanism of natural enzymes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431203

New algorithms and an in silico benchmark for computational enzyme design

27 September 2017

1 reference

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ROSETTALIGAND: protein-small molecule docking with full side-chain flexibility.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1152692

Theoretical studies of stereoselectivities of intramolecular aldol cyclizations catalyzed by amino acids.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1152692

Catalytic Enantioselective Retro-Aldol Reactions: Kinetic Resolution of β-Hydroxyketones with Aldolase Antibodies

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18323453

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1152692

1 reference

793268

793268

1 reference

1 reference

1 reference