ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts (Q58699862)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30153289%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

title

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30153289%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

1 reference

0 references

14

1 reference

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20 April 2020

Ravesanker Ezhilarasan

18

1 reference

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20 April 2020

Michael D Blough

26

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20 April 2020

15

David R Kaplan

1 reference

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20 April 2020

25

J Gregory Cairncross

1 reference

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20 April 2020

author name string

Alice L Yuan

1

1 reference

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20 April 2020

Christian B Ricks

2

1 reference

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20 April 2020

Alexandra K Bohm

3

1 reference

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20 April 2020

Xueqing Lun

4

1 reference

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20 April 2020

Lori Maxwell

5

1 reference

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20 April 2020

Shahana Safdar

6

1 reference

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20 April 2020

Shazreh Bukhari

7

1 reference

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20 April 2020

Amanda Gerber

8

1 reference

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20 April 2020

Wajid Sayeed

9

1 reference

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20 April 2020

Elizabeth A Bering

10

1 reference

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20 April 2020

Haley Pedersen

11

1 reference

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20 April 2020

Jennifer A Chan

12

1 reference

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20 April 2020

Yaoqing Shen

13

1 reference

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20 April 2020

Warren Mason

16

1 reference

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20 April 2020

Lindsey D Goodman

17

1 reference

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20 April 2020

Ascher B Kaufmann

19

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20 April 2020

Matthew Cabral

20

1 reference

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20 April 2020

Steve M Robbins

21

1 reference

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20 April 2020

Donna L Senger

22

1 reference

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20 April 2020

Daniel P Cahill

23

1 reference

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20 April 2020

Erik P Sulman

24

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20 April 2020

language of work or name

English

0 references

publication date

28 August 2018

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20 April 2020

1 reference

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20 April 2020

volume

13

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20 April 2020

issue

8

1 reference

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20 April 2020

page(s)

e0202860

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Creative Commons Attribution 4.0 International

20 April 2020

copyright license

start time

28 August 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Evaluation of Concurrent Radiation, Temozolomide and ABT-888 Treatment Followed by Maintenance Therapy with Temozolomide and ABT-888 in a Genetically Engineered Glioblastoma Mouse Model

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ABT-888 enhances cytotoxic effects of temozolomide independent of MGMT status in serum free cultured glioma cells.

30 November 2018

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Novel MSH6 mutations in treatment-naïve glioblastoma and anaplastic oligodendroglioma contribute to temozolomide resistance independently of MGMT promoter methylation

30 November 2018

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A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a pediatric brain tumor consortium report

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Discordant in vitro and in vivo chemopotentiating effects of the PARP inhibitor veliparib in temozolomide-sensitive versus -resistant glioblastoma multiforme xenografts

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Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

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30 November 2018

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30 November 2018

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PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.

30 November 2018

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30 November 2018

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ABT-888 confers broad in vivo activity in combination with temozolomide in diverse tumors

30 November 2018

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MSH6 mutations arise in glioblastomas during temozolomide therapy and mediate temozolomide resistance.

30 November 2018

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Phase 0 clinical trial of the poly (ADP-ribose) polymerase inhibitor ABT-888 in patients with advanced malignancies

30 November 2018

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Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

30 November 2018

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Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines

30 November 2018

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30 November 2018

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Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks

30 November 2018

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Mismatch repair-dependent processing of methylation damage gives rise to persistent single-stranded gaps in newly replicated DNA.

30 November 2018

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30 November 2018

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ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models

30 November 2018

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Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment

30 November 2018

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30 November 2018

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Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft

30 November 2018

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The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death

30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

30 November 2018

1 reference

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Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma

30 November 2018

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Chk1 and Chk2 kinases in checkpoint control and cancer

30 November 2018

1 reference

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DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

30 November 2018

1 reference

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Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.

30 November 2018

1 reference

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Pharmacologic disruption of base excision repair sensitizes mismatch repair-deficient and -proficient colon cancer cells to methylating agents

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6112648

Involvement of the mismatch repair system in temozolomide-induced apoptosis.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6112648

The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6112648

Cell-cycle-dependent and ATM-independent expression of human Chk1 kinase

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30153289

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0202860

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30153289%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30153289%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

1 reference