Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood (Q57736683)

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article published in 2015

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English	Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood	article published in 2015

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scholarly article

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Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood (English)

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Alexander Perfilyev

object named as

A. Perfilyev

5

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object named as

L. Gillberg

3

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Elisabet Stener-Victorin

object named as

E. Stener-Victorin

14

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object named as

T. Hansen

12

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Oluf Borbye Pedersen

object named as

O. Pedersen

11

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object named as

C. Ling

17

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13

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L. Groop

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author name string

T. Ronn

1

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P. Volkov

2

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M. Kokosar

4

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A. L. Jacobsen

6

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S. W. Jorgensen

7

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C. Brons

8

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P.-A. Jansson

9

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K.-F. Eriksson

10

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A. Vaag

15

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E. Nilsson

16

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publication date

10 April 2015

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Human Molecular Genetics

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Epigenetics: a molecular link between environmental factors and type 2 diabetes

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Epigenetic differences arise during the lifetime of monozygotic twins

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DNA methylation profiles in monozygotic and dizygotic twins.

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Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes

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Genome-wide analysis of DNA methylation differences in muscle and fat from monozygotic twins discordant for type 2 diabetes

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Insufficient DNA methylation affects healthy aging and promotes age-related health problems

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A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue

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Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a 6-month exercise intervention

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Genetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscle

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Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle

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Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

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Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.

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Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

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Role of epigenetic mechanisms in the vascular complications of diabetes.

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Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets

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Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes

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Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner

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First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal Muscle

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Identifiers

10.1093/HMG/DDV124

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