Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer. (Q33762434)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20219944%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer (English)

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19 January 2020

0 references

8

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19 January 2020

Usha Menon

2

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19 January 2020

Susan J. Ramus

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19 January 2020

Christopher G Bell

9

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19 January 2020

Peter Maxwell

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19 January 2020

Ian Jacobs

20

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19 January 2020

Martin Widschwendter

21

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19 January 2020

15

Simon A Gayther

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Aleksandra Gentry-Maharaj

19 January 2020

3

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Aleksandra Gentry-Maharaj

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19 January 2020

19

Peter W Laird

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19 January 2020

Andrew E Teschendorff

1

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Andrew E Teschendorff

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19 January 2020

Daniel J Weisenberger

5

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Daniel J Weisenberger

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19 January 2020

author name string

Hui Shen

6

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19 January 2020

Mihaela Campan

7

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19 January 2020

David A Savage

11

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19 January 2020

Elisabeth Mueller-Holzner

12

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19 January 2020

Christian Marth

13

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19 January 2020

Gabrijela Kocjan

14

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19 January 2020

Allison Jones

16

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19 January 2020

Stephan Beck

17

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19 January 2020

Wolfgang Wagner

18

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19 January 2020

publication date

10 March 2010

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19 January 2020

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19 January 2020

volume

20

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19 January 2020

page(s)

440-446

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19 January 2020

issue

4

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An epigenetic signature in peripheral blood predicts active ovarian cancer

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

DNA Damage, Aging, and Cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Loss of GATA4 and GATA6 expression specifies ovarian cancer histological subtypes and precedes neoplastic transformation of ovarian surface epithelia

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

A general framework for multiple testing dependence

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Cell type-specific DNA methylation patterns in the human breast

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Intra-individual change over time in DNA methylation with familial clustering

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

The emerging roles of forkhead box (Fox) proteins in cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

PubMeth: a cancer methylation database combining text-mining and expert annotation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Capturing heterogeneity in gene expression studies by surrogate variable analysis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Epigenetics and aging: the targets and the marks

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Cross-talk between aging and cancer: the epigenetic language

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Epigenetic stem cell signature in cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Control of developmental regulators by Polycomb in human embryonic stem cells

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Histone modifications silence the GATA transcription factor genes in ovarian cancer

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

High-throughput DNA methylation profiling using universal bead arrays

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Involvement of GATA-4/-5 transcription factors in ovarian carcinogenesis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

5-Lipoxygenase regulates senescence-like growth arrest by promoting ROS-dependent p53 activation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

p63 and p73: roles in development and tumor formation

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Statistical significance for genomewide studies

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Role for the p53 homologue p73 in E2F-1-induced apoptosis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression.

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

DNA hypomethylation and ovarian cancer biology.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2847747

Anomalous expression of epithelial differentiation-determining GATA factors in ovarian tumorigenesis

30 October 2018

1 reference

12 December 2020

Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon

1 reference

12 December 2020

Aging and DNA methylation in colorectal mucosa and cancer

1 reference

12 December 2020

p73 suppresses polyploidy and aneuploidy in the absence of functional p53

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1101/GR.103606.109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20219944%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20219944%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference