Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis (Q56914273)

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25 December 2019

title

Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis (English)

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25 December 2019

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Roisin Mcmahon

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Yvonne Jones

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Lars Fugger

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25 December 2019

author name string

Karen B Jakobsen

2

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Lone Friis

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Ruth Etzensperger

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Matthew J Craner

5

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Lise T Jensen

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Véronique Huygelen

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John I Bell

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language of work or name

English

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publication date

26 October 2008

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25 December 2019

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25 December 2019

volume

14

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issue

11

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25 December 2019

page(s)

1227-1235

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https://scigraph.springernature.com/pub.10.1038/nm.1881

25 December 2019

exact match

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cites work

Regulatory functions of CD8+CD28– T cells in an autoimmune disease model

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Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice.

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Monoclonal antibody treatment exposes three mechanisms underlying the clinical course of multiple sclerosis

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The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisal

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7 January 2021

The role of CD8(+) T cells in multiple sclerosis and its animal models

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7 January 2021

Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

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7 January 2021

Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesions.

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7 January 2021

Immunohistological analysis of T lymphocyte subsets in the central nervous system in chronic progressive multiple sclerosis.

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7 January 2021

Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction

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7 January 2021

Multiple sclerosis: T-cell receptor expression in distinct brain regions

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7 January 2021

A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

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7 January 2021

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

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7 January 2021

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

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7 January 2021

Role of CD8+ T cells in murine experimental allergic encephalomyelitis

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A high-density screen for linkage in multiple sclerosis

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7 January 2021

Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group

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7 January 2021

Histocompatibility determinants in multiple sclerosis, with special reference to clinical course

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7 January 2021

Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia

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7 January 2021

Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis

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7 January 2021

Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease

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7 January 2021

Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis.

1 reference

7 January 2021

HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis

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7 January 2021

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis

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7 January 2021

Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium

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7 January 2021

The future of genetic studies of complex human diseases

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7 January 2021

Adaptation of the extended transmission/disequilibrium test to distinguish disease associations of multiple loci: the Conditional Extended Transmission/Disequilibrium Test

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7 January 2021

Functional epistasis on a common MHC haplotype associated with multiple sclerosis

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7 January 2021

Identification of an epitope derived from human proteolipid protein that can induce autoreactive CD8+ cytotoxic T lymphocytes restricted by HLA-A3: evidence for cross-reactivity with an environmental microorganism

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7 January 2021

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

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7 January 2021

Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain

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7 January 2021

Receptor editing in developing T cells

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7 January 2021

Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor alpha-chain locus

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7 January 2021

Increased reactivity to myelin oligodendrocyte glycoprotein peptides and epitope mapping in HLA DR2(15)+ multiple sclerosis

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7 January 2021

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

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7 January 2021

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

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7 January 2021

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

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7 January 2021

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

1 reference

7 January 2021

Central tolerance: learning self-control in the thymus

1 reference

7 January 2021

Aire regulates negative selection of organ-specific T cells

1 reference

7 January 2021

HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout mice

1 reference

7 January 2021

Analysis of the HLA-restricted influenza-specific cytotoxic T lymphocyte response in transgenic mice carrying a chimeric human-mouse class I major histocompatibility complex

1 reference

7 January 2021

Mice lacking all conventional MHC class II genes

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM.1881

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18953350%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

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