Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes (Q56902091)

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object named as

R Veijola

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author name string

R Hermann

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K Lipponen

2

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M Kiviniemi

3

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T Kakko

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O Simell

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J Ilonen

https://scigraph.springernature.com/pub.10.1007/s00125-006-0225-4

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language of work or name

English

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publication date

June 2006

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published in

Diabetologia

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volume

49

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issue

6

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page(s)

1198-208

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exact match

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cites work

Pathologic anatomy of the pancreas in juvenile diabetes mellitus

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-006-0225-4

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

21 January 2018

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12 December 2020

Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus

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Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children

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HLA class II associated risk and protection against multiple sclerosis-a Finnish family study

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Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation

1 reference

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Association of IA-2 autoantibodies with HLA DR4 phenotypes in IDDM

1 reference

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Population-based genetic screening for the estimation of Type 1 diabetes mellitus risk in Finland: selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci

1 reference

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A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients

1 reference

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Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.

1 reference

12 December 2020

A novel micro-assay for insulin autoantibodies

1 reference

12 December 2020

Characterization of TCR-induced receptor-proximal signaling events negatively regulated by the protein tyrosine phosphatase PEP

1 reference

12 December 2020

Pedigree disequilibrium tests for multilocus haplotypes.

1 reference

12 December 2020

Disease-associated autoantibodies and HLA-DQB1 genotypes in children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). The Childhood Diabetes in Finland Study Group

1 reference

12 December 2020

Feasibility of genetic and immunological prediction of type I diabetes in a population-based birth cohort

1 reference

12 December 2020

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

1 reference

12 December 2020

Genetic screening for individuals at high risk for type 1 diabetes in the general population using HLA Class II alleles as disease markers. A comparison between three European populations with variable rates of disease incidence

1 reference

12 December 2020

IA-2 antibodies--a sensitive marker of IDDM with clinical onset in childhood and adolescence. Childhood Diabetes in Finland Study Group.

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12 December 2020

Genetics of type 1 diabetes mellitus

1 reference

12 December 2020

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

1 reference

12 December 2020

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

1 reference

12 December 2020

Associations of GAD65- and IA-2- autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. The Belgian Diabetes Registry

1 reference

12 December 2020

IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.

1 reference

12 December 2020

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

1 reference

12 December 2020

The codon 620 tryptophan allele of the lymphoid tyrosine phosphatase (LYP) gene is a major determinant of Graves' disease

1 reference

12 December 2020

Triple-label hybridization assay for type-1 diabetes-related HLA alleles

1 reference

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Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population

1 reference

12 December 2020

Type 1 diabetes is insulin -2221 MspI and CTLA-4 +49 A/G polymorphism dependent

1 reference

12 December 2020

CTLA-4 gene polymorphism confers susceptibility to insulin-dependent diabetes mellitus (IDDM) independently from age and from other genetic or immune disease markers. The Belgian Diabetes Registry

1 reference

12 December 2020

Pregnancy induces nonimmunoglobulin insulin-binding activity in both maternal and cord blood serum

1 reference

12 December 2020

The HLA class I A locus affects susceptibility to type 1 diabetes

1 reference

12 December 2020

Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci

1 reference

12 December 2020

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

1 reference

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HLA DR-DQ-encoded genetic determinants of childhood-onset type 1 diabetes in Finland: an analysis of 622 nuclear families

1 reference

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Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes

1 reference

12 December 2020

Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population

1 reference

12 December 2020

Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study

1 reference

12 December 2020

Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B

1 reference

12 December 2020

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

1 reference

12 December 2020

T-cell clones from a type-1 diabetes patient respond to insulin secretory granule proteins

1 reference

12 December 2020

The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity

1 reference

12 December 2020

A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families

1 reference

12 December 2020

Successful prospective prediction of type 1 diabetes in schoolchildren through multiple defined autoantibodies: an 8-year follow-up of the Washington State Diabetes Prediction Study

1 reference

12 December 2020

HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection

1 reference

12 December 2020

Natural history of beta-cell autoimmunity in young children with increased genetic susceptibility to type 1 diabetes recruited from the general population

1 reference

12 December 2020

Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes

1 reference

12 December 2020

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

1 reference

12 December 2020

A homogeneous high-throughput genotyping method based on competitive hybridization

1 reference

12 December 2020

Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase

1 reference

12 December 2020

Remapping the insulin gene/IDDM2 locus in type 1 diabetes.

1 reference

12 December 2020