GLI family zinc finger 3 (Q5513621)

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mammalian protein found in Homo sapiens
  • GLI-Kruppel family member GLI3
  • GLI3 form of 190 kDa
  • GLI3-190
  • GLI3FL
  • glioma-associated oncogene family zinc finger 3
  • GLI3
  • transcriptional activator GLI3
  • oncogene GLI3
  • zinc finger protein GLI3
  • GLI3 full length protein
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Language Label Description Also known as
English
GLI family zinc finger 3
mammalian protein found in Homo sapiens
  • GLI-Kruppel family member GLI3
  • GLI3 form of 190 kDa
  • GLI3-190
  • GLI3FL
  • glioma-associated oncogene family zinc finger 3
  • GLI3
  • transcriptional activator GLI3
  • oncogene GLI3
  • zinc finger protein GLI3
  • GLI3 full length protein

Statements

molecular function
protein binding
determination method
IPI
16 references
retrieved
8 April 2019
stated in
Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of the interactions of human ZIC3 mutants with GLI3
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Mediator modulates Gli3-dependent Sonic hedgehog signaling
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Physical and functional interactions between Zic and Gli proteins
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Gli regulation by the opposing activities of fused and suppressor of fused
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Physical and functional interactions between Zic and Gli proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
retrieved
8 April 2019
stated in
Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IEA
retrieved
8 April 2019
stated in
Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IDA
retrieved
8 April 2019
stated in
Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IDA
retrieved
8 April 2019
stated in
Physical and functional interactions between Zic and Gli proteins
GOA
curator
UniProt
UniProt protein ID
P10071
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IDA
retrieved
8 April 2019
stated in
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IDA
retrieved
8 April 2019
stated in
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10071
determination method
IDA
biological process
Gene Atlas image
PBB GE GLI3 205201 at fs.png
732 × 530; 12 KB
0 references

Identifiers

 
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