Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase (Q37482039)

20 August 2017

Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase (English)

1 reference

Speckle-type BTB/POZ protein

20 August 2017

1 reference

GLI-Kruppel family member GLI2

1 reference

Roadkill Dmel_CG12537

1 reference

Suppressor of fused Dmel_CG6054

1 reference

Cubitus interruptus Dmel_CG2125

1 reference

author name string

Qing Zhang

1

1 reference

20 August 2017

Qing Shi

2

1 reference

20 August 2017

Yongbin Chen

3

1 reference

20 August 2017

Tao Yue

4

1 reference

20 August 2017

Shuang Li

5

1 reference

20 August 2017

Bing Wang

6

1 reference

20 August 2017

Jin Jiang

7

1 reference

20 August 2017

language of work or name

English

0 references

publication date

2 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

1 reference

20 August 2017

106

1 reference

20 August 2017

50

1 reference

20 August 2017

21191-21196

1 reference

Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer.

20 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Transducing the Hedgehog signal across the plasma membrane

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Regulation of Hh/Gli signaling by dual ubiquitin pathways

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

The KLHL12-Cullin-3 ubiquitin ligase negatively regulates the Wnt-beta-catenin pathway by targeting Dishevelled for degradation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Cullin-based ubiquitin ligases: Cul3-BTB complexes join the family.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

A protein interaction map of Drosophila melanogaster

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

SCF and Cullin/Ring H2-based ubiquitin ligases

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Crystal structure of the BTB domain from PLZF

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Cooperative requirement of the Gli proteins in neurogenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Regulation of Ci-SCFSlimb binding, Ci proteolysis, and hedgehog pathway activity by Ci phosphorylation.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Dual degradation signals control Gli protein stability and tumor formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Regulation of the Drosophila transcription factor, Cubitus interruptus, by two conserved domains

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

The N-terminal POZ domain of GAGA mediates the formation of oligomers that bind DNA with high affinity and specificity

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Co-operative DNA binding by GAGA transcription factor requires the conserved BTB/POZ domain and reorganizes promoter topology

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Protein kinase A and hedgehog signaling in Drosophila limb development

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2795488

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

26 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912008106

Phosphorylation by double-time/CKIepsilon and CKIalpha targets cubitus interruptus for Slimb/beta-TRCP-mediated proteolytic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912008106

Processing of the Drosophila hedgehog signaling effector Ci-155 to the repressor Ci-75 is mediated by direct binding to the SCF component Slimb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912008106

Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912008106

A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912008106

Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912008106

Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912008106

Fluorescence resonance energy transfer imaging microscopy

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19955409

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0912008106

1 reference

20 August 2017

0 references

1 reference

20 August 2017

1 reference