Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling. (Q54677795)

2 June 2018

title

Insulin analogues differently activate insulin receptor isoforms and post-receptor signalling. (English)

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7

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Marco Genua

object named as

M Genua

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Laura Sciacca

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object named as

L Sciacca

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2 June 2018

author name string

M F Cassarino

2

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G Pandini

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R Le Moli

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S Squatrito

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publication date

28 April 2010

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published in

Diabetologia

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volume

53

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issue

8

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page(s)

1743-1753

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https://scigraph.springernature.com/pub.10.1007/s00125-010-1760-6

exact match

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cites work

Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells.

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00125-010-1760-6

Critical nodes in signalling pathways: insights into insulin action

21 January 2018

1 reference

12 December 2020

Insulin and its analogue glargine do not affect viability and proliferation of human coronary artery endothelial and smooth muscle cells

1 reference

12 December 2020

Modifications in the B10 and B26-30 regions of the B chain of human insulin alter affinity for the human IGF-I receptor more than for the insulin receptor

1 reference

12 December 2020

Glargine blood biotransformation: in vitro appraisal with human insulin immunoassay

1 reference

12 December 2020

Growth promoting and metabolic activity of the human insulin analogue [GlyA21,ArgB31,ArgB32]insulin (HOE 901) in muscle cells

1 reference

12 December 2020

Mitogenic effect of the insulin analogue glargine in malignant cells in comparison with insulin and IGF-I.

1 reference

12 December 2020

A novel insulin analog with unique properties: LysB3,GluB29 insulin induces prominent activation of insulin receptor substrate 2, but marginal phosphorylation of insulin receptor substrate 1.

1 reference

12 December 2020

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12 December 2020

Insulin glargine and cancer--an unsubstantiated allegation

1 reference

12 December 2020

Proliferation of colo-357 pancreatic carcinoma cells and survival of patients with pancreatic carcinoma are not altered by insulin glargine

1 reference

12 December 2020

A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer

1 reference

12 December 2020

Sustained signalling from the insulin receptor after stimulation with insulin analogues exhibiting increased mitogenic potency

1 reference

12 December 2020

Characteristics of signalling properties mediated by long-acting insulin analogue glargine and detemir in target cells of insulin.

1 reference

12 December 2020

ASPB10 insulin induction of increased mitogenic responses and phenotypic changes in human breast epithelial cells: evidence for enhanced interactions with the insulin-like growth factor-I receptor

1 reference

12 December 2020

Human aortic smooth muscle cells are insulin resistant at the receptor level but sensitive to IGF1 and IGF2.

1 reference

12 December 2020

The long acting human insulin analog HOE 901: characteristics of insulin signalling in comparison to Asp(B10) and regular insulin

1 reference

12 December 2020

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12 December 2020

Insulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cells

1 reference

12 December 2020

Soluble, fatty acid acylated insulins bind to albumin and show protracted action in pigs

1 reference

12 December 2020

Differential signaling activation by insulin and insulin-like growth factors I and II upon binding to insulin receptor isoform A.

1 reference

12 December 2020

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

1 reference

12 December 2020

Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/paracrine mechanism

1 reference

12 December 2020

Insulin analogues and carcinoma of the breast

1 reference

12 December 2020

Molecular mechanisms of differential intracellular signaling from the insulin receptor

1 reference

12 December 2020

Comparison of the mitogenic potency of regular human insulin and its analogue glargine in normal and transformed human breast epithelial cells

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12 December 2020

Effects of the long-acting insulin analog insulin glargine on cultured human skeletal muscle cells: comparisons to insulin and IGF-I.

1 reference

12 December 2020

Functionally distinct insulin receptors generated by tissue-specific alternative splicing

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12 December 2020

Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines.

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12 December 2020

The bioactivity of insulin analogues from in vitro receptor binding to in vivo glucose uptake

1 reference

12 December 2020

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12 December 2020

Mitogenic properties of insulin and insulin analogues mediated by the insulin receptor

1 reference

12 December 2020

Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use

1 reference

12 December 2020

IGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts.

1 reference

12 December 2020

Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling

1 reference

12 December 2020

Recombinant DNA technology in the treatment of diabetes: insulin analogs

1 reference

12 December 2020

Does diabetes therapy influence the risk of cancer?

1 reference

12 December 2020

10.1007/S00125-010-1760-6

Identifiers

DOI

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2 June 2018

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2 June 2018