Interleukin-2/anti-interleukin-2 monoclonal antibody immune complex suppresses collagen-induced arthritis in mice by fortifying interleukin-2/STAT5 signalling pathways. (Q54470592)

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English	Interleukin-2/anti-interleukin-2 monoclonal antibody immune complex suppresses collagen-induced arthritis in mice by fortifying interleukin-2/STAT5 signalling pathways.	scientific article

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scholarly article

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Europe PubMed Central

30 May 2018

http://europepmc.org/abstract/MED/23167249

Interleukin-2/anti-interleukin-2 monoclonal antibody immune complex suppresses collagen-induced arthritis in mice by fortifying interleukin-2/STAT5 signalling pathways. (English)

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Europe PubMed Central

30 May 2018

http://europepmc.org/abstract/MED/23167249

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object named as

Charles D Surh

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30 May 2018

http://europepmc.org/abstract/MED/23167249

author name string

Seon-Yeong Lee

1

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http://europepmc.org/abstract/MED/23167249

Mi-La Cho

2

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http://europepmc.org/abstract/MED/23167249

Hye-Jwa Oh

3

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http://europepmc.org/abstract/MED/23167249

Jun-Geol Ryu

4

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http://europepmc.org/abstract/MED/23167249

Min-Jung Park

5

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http://europepmc.org/abstract/MED/23167249

Joo-Yeon Jhun

6

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http://europepmc.org/abstract/MED/23167249

Mi-Kyung Park

7

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http://europepmc.org/abstract/MED/23167249

John C Stone

8

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http://europepmc.org/abstract/MED/23167249

Ji-Hyun Ju

9

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http://europepmc.org/abstract/MED/23167249

Sue-Yun Hwang

10

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http://europepmc.org/abstract/MED/23167249

Sung-Hwan Park

11

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Ho-Youn Kim

13

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publication date

1 December 2012

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http://europepmc.org/abstract/MED/23167249

137

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4

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305-316

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http://europepmc.org/abstract/MED/23167249

The role of interleukin-2 during homeostasis and activation of the immune system

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25 August 2018

Foxp3+ follicular regulatory T cells control the germinal center response.

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Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

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25 August 2018

T regulatory cells participate in the control of germinal centre reactions.

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Suppressors of cytokine signaling (SOCS) proteins and JAK/STAT pathways: regulation of T-cell inflammation by SOCS1 and SOCS3.

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Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

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Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

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25 August 2018

IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25

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IL-17 as a future therapeutic target for rheumatoid arthritis

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Control of regulatory T cell lineage commitment and maintenance

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IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets

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In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

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The biocompatible polysaccharide chitosan enhances the oral tolerance to type II collagen.

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CTLA-4 control over Foxp3+ regulatory T cell function

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The regulatory, inflammatory, and T cell programming roles of interleukin-2 (IL-2).

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Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment

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25 August 2018

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

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25 August 2018

Nonredundant roles for Stat5a/b in directly regulating Foxp3

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25 August 2018

Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease

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25 August 2018

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

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25 August 2018

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

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25 August 2018

A unique role for Stat5 in recovery from acute anemia

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Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

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Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.

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25 August 2018

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

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25 August 2018

The role of T-cell interleukin-17 in conducting destructive arthritis: lessons from animal models

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25 August 2018

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

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25 August 2018

The regulatory T cell family: distinct subsets and their interrelations

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25 August 2018

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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25 August 2018

Control of regulatory T cell development by the transcription factor Foxp3

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25 August 2018

Identification of regulatory T cells in tolerated allografts

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25 August 2018

Suppression of collagen-induced arthritis by single administration of poly(lactic-co-glycolic acid) nanoparticles entrapping type II collagen: a novel treatment strategy for induction of oral tolerance

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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25 August 2018

IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis

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Induction of arthritis with monoclonal antibodies to collagen

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25 August 2018

Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice

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12 December 2020

based on heuristic

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IL-1-independent role of IL-17 in synovial inflammation and joint destruction during collagen-induced arthritis

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12 December 2020

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IL-17 promotes bone erosion in murine collagen-induced arthritis through loss of the receptor activator of NF-kappa B ligand/osteoprotegerin balance

1 reference

https://pubmed.ncbi.nlm.nih.gov/23167249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

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https://pubmed.ncbi.nlm.nih.gov/23167249

12 December 2020

based on heuristic

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Emerging challenges in regulatory T cell function and biology

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12 December 2020

based on heuristic

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Serum and synovial fluid levels of interleukin-17 in correlation with disease activity in patients with RA

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https://pubmed.ncbi.nlm.nih.gov/23167249

12 December 2020

based on heuristic

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CD25+ T(reg) specifically suppress auto-Ab generation against pancreatic tissue autoantigens

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https://pubmed.ncbi.nlm.nih.gov/23167249

12 December 2020

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Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells

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https://pubmed.ncbi.nlm.nih.gov/23167249

12 December 2020

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Heterogeneous effects of IL-2 on collagen-induced arthritis

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https://pubmed.ncbi.nlm.nih.gov/23167249

12 December 2020

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Identifiers

10.1111/IMM.12008

1 reference

Europe PubMed Central

30 May 2018

http://europepmc.org/abstract/MED/23167249

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1 reference

Europe PubMed Central

30 May 2018

http://europepmc.org/abstract/MED/23167249

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