IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25 (Q33719745)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25 (English)

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17 January 2020

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3

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17 January 2020

Onur Boyman

8

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17 January 2020

5

Giuseppe Pantaleo

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17 January 2020

6

Jonathan Sprent

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17 January 2020

7

Charles D Surh

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17 January 2020

author name string

Sven Létourneau

1

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17 January 2020

Ester M M van Leeuwen

2

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17 January 2020

Chris Martin

4

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17 January 2020

publication date

19 January 2010

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Proceedings of the National Academy of Sciences of the United States of America

17 January 2020

published in

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17 January 2020

volume

107

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17 January 2020

issue

5

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17 January 2020

page(s)

2171-2176

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IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets

17 January 2020

cites work

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Naive CD8+ T cells differentiate into protective memory-like cells after IL-2 anti IL-2 complex treatment in vivo

21 June 2018

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21 June 2018

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Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease

21 June 2018

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21 June 2018

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21 June 2018

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

21 June 2018

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Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells

21 June 2018

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FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses

21 June 2018

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Heparan sulfate proteoglycans mediate interleukin-7-dependent B lymphopoiesis

21 June 2018

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Interaction of interleukin 7 (IL-7) with glycosaminoglycans and its biological relevance

21 June 2018

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The IL-2 receptor complex: its structure, function, and target genes

21 June 2018

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Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signalling

21 June 2018

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Specific targeting and killing activities of anti-P-glycoprotein monoclonal antibody MRK16 directed against intrinsically multidrug-resistant human colorectal carcinoma cell lines in the nude mouse model

21 June 2018

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21 June 2018

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21 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0909384107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20133862%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

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17 January 2020

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