Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK. (Q54295628)

27 May 2018

title

Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK. (English)

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27 May 2018

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11

Joseph Schlessinger

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27 May 2018

Phillip B Murray

1

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27 May 2018

Irit Lax

2

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27 May 2018

Andrey Reshetnyak

3

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27 May 2018

Gwenda F Ligon

4

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27 May 2018

Jay S Lillquist

5

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27 May 2018

Edward J Natoli

6

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27 May 2018

Xiarong Shi

7

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27 May 2018

Ewa Folta-Stogniew

8

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27 May 2018

Murat Gunel

9

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27 May 2018

Diego Alvarado

10

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27 May 2018

publication date

20 January 2015

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27 May 2018

published in

Science Signaling

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27 May 2018

volume

8

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27 May 2018

page(s)

ra6

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27 May 2018

issue

360

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27 May 2018

The genetic landscape of high-risk neuroblastoma

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Mechanistic insight into ALK receptor tyrosine kinase in human cancer biology

21 January 2018

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Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Expression and functional analysis of the anaplastic lymphoma kinase (ALK) gene in tumor cell lines

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

In contrast to agonist monoclonal antibodies, both C-terminal truncated form and full length form of Pleiotrophin failed to activate vertebrate ALK (anaplastic lymphoma kinase)?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Activation and inhibition of anaplastic lymphoma kinase receptor tyrosine kinase by monoclonal antibodies and absence of agonist activity of pleiotrophin.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Cell signaling by receptor tyrosine kinases

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Protein structure prediction on the Web: a case study using the Phyre server

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Kinetic model for FGF, FGFR, and proteoglycan signal transduction complex assembly

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Proteoglycan-Specific Molecular Switch for RPTP Clustering and Neuronal Extension

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Heparin and heparan sulfate: structure and function

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

Anaplastic lymphoma kinase spares organ growth during nutrient restriction in Drosophila.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

PCR-mediated deletion of plasmid DNA.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCISIGNAL.2005916

10.1126/SCISIGNAL.2005916

21 January 2018

Identifiers

DOI

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27 May 2018

PubMed ID

25605972

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27 May 2018