INK4a/Arf is required for suppression of EGFR/DeltaEGFR(2-7)-dependent ERK activation in mouse astrocytes and glioma. (Q53890346)

22 May 2018

title

INK4a/Arf is required for suppression of EGFR/DeltaEGFR(2-7)-dependent ERK activation in mouse astrocytes and glioma. (English)

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22 May 2018

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8

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22 May 2018

author name string

Yan Lachat

1

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22 May 2018

Annie-Claire Diserens

2

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22 May 2018

Michimasa Nozaki

3

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22 May 2018

Hiroyuki Kobayashi

4

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22 May 2018

Marie-France Hamou

5

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22 May 2018

Sophie Godard

6

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22 May 2018

Nicolas De Tribolet

7

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22 May 2018

language of work or name

English

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publication date

1 September 2004

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22 May 2018

published in

Oncogene

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22 May 2018

volume

23

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22 May 2018

issue

41

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22 May 2018

page(s)

6854-6863

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22 May 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207872

exact match

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cites work

The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Regulation of anoikis by Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Split personalities: the agonistic antagonist Sprouty

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Characterization of an established human malignant glioma cell line: LN-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Cluster analysis and display of genome-wide expression patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Role of cell shape in growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

p53 gene mutation and ink4a-arf deletion appear to be two mutually exclusive events in human glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Coupled two-way clustering analysis of gene microarray data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Proliferation of human malignant astrocytomas is dependent on Ras activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Hemizygous or homozygous deletion of the chromosomal region containing the p16INK4a gene is associated with amplification of the EGF receptor gene in glioblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Quantitative real-time PCR does not show selective targeting of p14(ARF) but concomitant inactivation of both p16(INK4A) and p14(ARF) in 105 human primary gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

The EGF receptor family as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Expression of constitutively activated EGFRvIII in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Oncogenic Ras and Akt Signaling Contribute to Glioblastoma Formation by Differential Recruitment of Existing mRNAs to Polysomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Phase II trial of gefitinib in recurrent glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

The RB and p53 pathways in cancer

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1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Structural alterations of the epidermal growth factor receptor gene in human gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Epidermal growth factor receptor and Ink4a/Arf

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Activation of ARF by oncogenic stress in mouse fibroblasts is independent of E2F1 and E2F2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

Coupled two-way clustering server

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

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Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation?

1 reference

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A safe packaging line for gene transfer: separating viral genes on two different plasmids

1 reference

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Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207872

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207872

1 reference

22 May 2018

PubMed ID

15273738

1 reference

22 May 2018